Varaico: Literature-Extracted Genetic Variants

Gene:ERBB2
Variant:p.N1219S
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ERBB2

NM_004448.4:p.N1219S

Associated Papers

Integrating evidence from protein domains to identify cancer driver mutations.

Ostroverkhova D et al.

Protein Science : a Publication of the Protein Society, 2026

41556616 (PubMed )
Supplement: PRO-35-e70422-s002.xlsx › Table_S1

ERBB2-Mutant Gastrointestinal Tumors Represent Heterogeneous Molecular Biology, Particularly in Microsatellite Instability, Tumor Mutation Burden, and Co-Mutated Genes: An In Silico Study.

Uchida S et al.

Current Issues in Molecular Biology, 2023

37754252 (PubMed )
Supplement: cimb-45-00468-s001.zip › Table_S1.xlsx › Sheet1

ERBB family fusions are recurrent and actionable oncogenic targets across cancer types.

Schubert L et al.

Frontiers in Oncology, 2023

37168365 (PubMed )
Supplement: Table_4.xlsx › ERBB2_mutations

Pan-Cancer Landscape and Analysis of ERBB2 Mutations Identifies Poziotinib as a Clinically Active Inhibitor and Enhancer of T-DM1 Activity.

Robichaux JP et al.

Cancer Cell, 2019

HER2 activating mutations are targets for colorectal cancer treatment.

Kavuri SM et al.

Cancer Discovery, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."