Varaico: Literature-Extracted Genetic Variants

Gene:ERBB3
Variant:p.T355A
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ERBB3

NM_001982.4:p.T355A

Associated Papers

Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.

Sakthikumar S et al.

Veterinary and Comparative Oncology, 2023

37248814 (PubMed )
Supplement: supplement_1.xlsx › Supp._Table_5

High prevalence of somatic PIK3CA and TP53 pathogenic variants in the normal mammary gland tissue of sporadic breast cancer patients revealed by duplex sequencing.

Kostecka A et al.

Npj Breast Cancer, 2022

35768433 (PubMed )
Supplement: 41523_2022_443_MOESM6_ESM.xlsx › Non_-_truncating_variants

Co-occurring gain-of-function mutations in HER2 and HER3 modulate HER2/HER3 activation, oncogenesis, and HER2 inhibitor sensitivity.

Hanker AB et al.

Cancer Cell, 2021

Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.

Pandey A et al.

Nature Communications, 2020

32839463 (PubMed )
Supplement: 41467_2020_17880_MOESM1_ESM.pdf

ERBB3 mutations in cancer: biological aspects, prevalence and therapeutics.

Kiavue N et al.

Oncogene, 2020

Activating HER3 mutations in breast cancer.

Mishra R et al.

Oncotarget, 2018

Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.

Ross JS et al.

Cancer, 2018

HER kinase inhibition in patients with HER2- and HER3-mutant cancers.

Hyman DM et al.

Nature, 2018

Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer.

Elster N et al.

Therapeutic Advances in Medical Oncology, 2018

30023006 (PubMed )
Supplement: Supplementary_material.pdf

A germline ERBB3 variant is a candidate for predisposition to erythroid MDS/erythroleukemia.

Braunstein EM et al.

Leukemia, 2016

Oncogenic ERBB3 mutations in human cancers.

Jaiswal BS et al.

Cancer Cell, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."