Varaico: Literature-Extracted Genetic Variants

Gene:ERBB3
Variant:p.E542K
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ERBB3

NM_001982.4:p.E542K

Associated Papers

Profiling of HER2, KRAS, and PIK3CA mutations in uterine cervical neuroendocrine carcinoma and implications for oncogenic driver targeting therapy.

Chao WR et al.

Cancer Genetics, 2025

MutationAssessor in cBioPortal.

Su Y et al.

Biorxiv : the Preprint Server for Biology, 2025

Identification of Somatic Genetic Variants in Superficial Vascular Malformations by Liquid Biopsy in a Cohort of 88 Patients from a French Hospital.

El Sissy FN et al.

Molecular Diagnosis & Therapy, 2025

Molecular characteristics of advanced colorectal cancer and multi-hit PIK3CA mutations.

Yasin F et al.

The Oncologist, 2024

Unveiling the role of PIK3R1 in cancer: A comprehensive review of regulatory signaling and therapeutic implications.

Gupta I et al.

Seminars in Cancer Biology, 2024

Molecular characterization of Chinese patients with small bowel adenocarcinoma.

Jin B et al.

Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2024

Variation Analysis in Premenopausal and Postmenopausal Breast Cancer Cases.

Erdogdu IH et al.

Journal of Personalized Medicine, 2024

Concordance of Targeted Sequencing from Circulating Tumor DNA and Paired Tumor Tissue for Early Breast Cancer.

Huang CC et al.

Cancers, 2023

Clinicopathologic Characteristics and Outcomes for Patients With KRAS G12D-Mutant NSCLC.

Cooper AJ et al.

Jto Clinical and Research Reports, 2022

36118132 (PubMed )
Supplement: mmc2.docx

Sensitive and robust liquid biopsy-based detection of PIK3CA mutations in hormone-receptor-positive metastatic breast cancer patients.

Suppan C et al.

British Journal of Cancer, 2022

The Yin and Yang of ERBB4: Tumor Suppressor and Oncoprotein.

Lucas LM et al.

Pharmacological Reviews, 2022

Precision medicine in breast cancer: From clinical trials to clinical practice.

Crimini E et al.

Cancer Treatment Reviews, 2021

Molecular patterns in salivary duct carcinoma identify prognostic subgroups.

Mueller SA et al.

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc, 2020

Signatures of somatic mutations and gene expression from p16INK4A positive head and neck squamous cell carcinomas (HNSCC).

Saba NF et al.

Plos One, 2020

Mutation profiling of cancer drivers in Brazilian colorectal cancer.

Dos Santos W et al.

Scientific Reports, 2019

Comparison of TCGA and GENIE genomic datasets for the detection of clinically actionable alterations in breast cancer.

Kaur P et al.

Scientific Reports, 2019

30728399 (PubMed )
Supplement: 41598_2018_37574_MOESM1_ESM.pdf

The distinct clinicopathological and prognostic implications of PIK3CA mutations in breast cancer patients from Central China.

Wu H et al.

Cancer Management and Research, 2019

Simultaneous identification of clinically relevant single nucleotide variants, copy number alterations and gene fusions in solid tumors by targeted next-generation sequencing.

Oliveira DM et al.

Oncotarget, 2018

Clinical implications of routine genomic mutation sequencing in PIK3CA/AKT1 and KRAS/NRAS/BRAF in metastatic breast cancer.

Cejalvo JM et al.

Breast Cancer Research and Treatment, 2016

Somatic Mutations of PI3K in Early and Advanced Gallbladder Cancer: Additional Options for an Orphan Cancer.

Roa I et al.

The Journal of Molecular Diagnostics : Jmd, 2016

Targeted capture massively parallel sequencing analysis of LCIS and invasive lobular cancer: Repertoire of somatic genetic alterations and clonal relationships.

Sakr RA et al.

Molecular Oncology, 2016

Comprehensive molecular characterization of gastric adenocarcinoma.

Unknown Author

Nature, 2014

The absence of the ERBB4 hotspot mutations in melanomas in patients from southern China.

Zhou QM et al.

Chinese Journal of Cancer, 2013

Molecular profiling of patients with colorectal cancer and matched targeted therapy in phase I clinical trials.

Dienstmann R et al.

Molecular Cancer Therapeutics, 2012

A growing family: adding mutated Erbb4 as a novel cancer target.

Rudloff U et al.

Cell Cycle (georgetown, Tex.), 2010

PIK3CA mutations in human solid tumors: role in sensitivity to various therapeutic approaches.

Ligresti G et al.

Cell Cycle (georgetown, Tex.), 2009

PIK3CA mutations are not a major determinant of resistance to the epidermal growth factor receptor inhibitor cetuximab in metastatic colorectal cancer.

Prenen H et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."