Varaico: Literature-Extracted Genetic Variants

Gene:ERBB3
Variant:p.S846I
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ERBB3

NM_001982.4:p.S846I

Associated Papers

Integrating evidence from protein domains to identify cancer driver mutations.

Ostroverkhova D et al.

Protein Science : a Publication of the Protein Society, 2026

41556616 (PubMed )
Supplement: PRO-35-e70422-s002.xlsx › Table_S1

HER3 V104 mutations regulate cell signaling, growth, and drug sensitivity in cancer.

Mishra R et al.

Molecular Carcinogenesis, 2024

Standing in the canine precision medicine knowledge gap: Improving annotation of canine cancer genomic biomarkers through systematic comparative analysis of human cancer mutations in COSMIC.

Sakthikumar S et al.

Veterinary and Comparative Oncology, 2023

37248814 (PubMed )
Supplement: supplement_1.xlsx › Supp._Table_5

Somatic Mutational Landscape in Mexican Patients: CDH1 Mutations and chr20q13.33 Amplifications Are Associated with Diffuse-Type Gastric Adenocarcinoma.

Cerrato-Izaguirre D et al.

International Journal of Molecular Sciences, 2022

36232418 (PubMed )
Supplement: ijms-23-11116-s001.zip › ijms-1877046-supplementary.pdf

Personalized cancer therapy prioritization based on driver alteration co-occurrence patterns.

Mateo L et al.

Genome Medicine, 2020

32907621 (PubMed )
Supplement: 13073_2020_774_MOESM1_ESM.zip › SupplementaryTables › TableS2.xlsx › Driver_Mutations

Integrated genomic analysis reveals mutated ELF3 as a potential gallbladder cancer vaccine candidate.

Pandey A et al.

Nature Communications, 2020

32839463 (PubMed )
Supplement: 41467_2020_17880_MOESM1_ESM.pdf

Next-Generation Sequencing Identifies Novel RTK VUSs in Breast Cancer with an Emphasis on ROS1, ERBB4, ALK and NTRK3.

Stein MK et al.

Pathology Oncology Research : Por, 2020

ERBB3 mutations in cancer: biological aspects, prevalence and therapeutics.

Kiavue N et al.

Oncogene, 2020

Classification of gastric cancer by EBV status combined with molecular profiling predicts patient prognosis.

He CY et al.

Clinical and Translational Medicine, 2020

32508039 (PubMed )
Supplement: CTM2-10-353-s003.xlsx › Table_S3

Analysis of error profiles in deep next-generation sequencing data.

Ma X et al.

Genome Biology, 2019

30867008 (PubMed )
Supplement: 13059_2019_1659_MOESM1_ESM.xlsx › S3_b

Comparison of TCGA and GENIE genomic datasets for the detection of clinically actionable alterations in breast cancer.

Kaur P et al.

Scientific Reports, 2019

30728399 (PubMed )
Supplement: 41598_2018_37574_MOESM1_ESM.pdf

Analysis on GENIE reveals novel recurrent variants that affect molecular diagnosis of sizable number of cancer patients.

Koyama T et al.

Bmc Cancer, 2019

30709382 (PubMed )
Supplement: 12885_2019_5313_MOESM2_ESM.xlsx › supplementary_2_filtered

Molecular Landscape of ERBB2/ERBB3 Mutated Colorectal Cancer.

Loree JM et al.

Journal of the National Cancer Institute, 2018

Targeting HER2 in colorectal cancer: The landscape of amplification and short variant mutations in ERBB2 and ERBB3.

Ross JS et al.

Cancer, 2018

Frequency, impact and a preclinical study of novel ERBB gene family mutations in HER2-positive breast cancer.

Elster N et al.

Therapeutic Advances in Medical Oncology, 2018

30023006 (PubMed )
Supplement: Supplementary_material.pdf

Successful immune checkpoint blockade in a patient with advanced stage microsatellite-unstable biliary tract cancer.

Czink E et al.

Cold Spring Harbor Molecular Case Studies, 2017

28619747 (PubMed )
Supplement: supp_mcs.a001974_Supplemental_Table_S1.pdf

Structure-functional prediction and analysis of cancer mutation effects in protein kinases.

Dixit A et al.

Computational and Mathematical Methods in Medicine, 2014

Oncogenic ERBB3 mutations in human cancers.

Jaiswal BS et al.

Cancer Cell, 2013

ERBB3 kinase domain mutations are rare in lung, breast and colon carcinomas.

Jeong EG et al.

International Journal of Cancer, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."