Varaico: Literature-Extracted Genetic Variants

Gene:ERCC2
Variant:p.R280H
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ERCC2

NM_000400.4:p.R280H

Associated Papers

Molecular Mechanisms of Preventable Causes of Oral Cancer and Precancer Through Polymorphism in DNA Base Excision Repair Genes in Patients with Tobacco Products Habits.

Sundaram E et al.

Journal of Maxillofacial and Oral Surgery, 2025

Genomic instability in ovarian cancer: Through the lens of single nucleotide polymorphisms.

Canchi Sistla H et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2025

Genetic polymorphisms and platinum-induced hematological toxicity: a systematic review.

Zheng Y et al.

Frontiers in Pharmacology, 2024

Single Nucleotide Polymorphisms in DNA Repair Genes (XRCC1, XRCC2, XRCC3) and Their Association with Radiotherapy Toxicity among Head and Neck Cancer Patients:A Study from South-Western Maharashtra.

Gudur AK et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2023

Genetic Polymorphisms Involved in Bladder Cancer: A Global Review.

Kourie HR et al.

Oncology Reviews, 2023

Impact of Polymorphism in Base Excision Repair and Nucleotide Excision Repair Genes and Risk of Cervical Cancer: A Case-Control Study.

Datkhile KD et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2022

Comprehensive germline genomic profiles of children, adolescents and young adults with solid tumors.

Akhavanfard S et al.

Nature Communications, 2020

32371905 (PubMed )
Supplement: 41467_2020_16067_MOESM12_ESM.xlsx › Supplementary_Data_7

Association between Single Nucleotide Polymorphisms and Glioma Risk: A Systematic Literature Review.

Tavares CB et al.

Cancer Investigation, 2020

The molecular genetics of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis.

Cliff J et al.

Critical Reviews in Oncology/hematology, 2017

Impact of DNA repair gene polymorphisms on the risk of biochemical recurrence after radiotherapy and overall survival in prostate cancer.

Zanusso C et al.

Oncotarget, 2017

28206966 (PubMed )
Supplement: oncotarget-08-22863-s001.pdf

The association of six non-synonymous variants in three DNA repair genes with hepatocellular carcinoma risk: a meta-analysis.

Shi YH et al.

Journal of Cellular and Molecular Medicine, 2016

Investigating the association between XRCC1 gene polymorphisms and susceptibility to gastric cancer.

Chen S et al.

Genetics and Molecular Research : Gmr, 2016

Identification and Functional Testing of ERCC2 Mutations in a Multi-national Cohort of Patients with Familial Breast- and Ovarian Cancer.

Rump A et al.

Plos Genetics, 2016

The association between four SNPs of X-ray repair cross complementing protein 1 and the sensitivity to radiotherapy in patients with esophageal squamous cell carcinoma.

Zhang Y et al.

Oncology Letters, 2016

Association of XRCC1 polymorphisms with arsenic methylation.

Fujihara J et al.

Archives of Toxicology, 2016

DNA repair pathway genes and lung cancer susceptibility: a meta-analysis.

Li W et al.

Gene, 2014

XRCC1 polymorphisms and cervical cancer risk: an updated meta-analysis.

Mei J et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

Molecular epidemiology of DNA repair gene polymorphisms and head and neck cancer.

Wang M et al.

Journal of Biomedical Research, 2013

Association between the XRCC1 Arg399Gln polymorphism and risk of cancer: evidence from 297 case-control studies.

Yi L et al.

Plos One, 2013

24205095 (PubMed )
Supplement: pone.0078071.s001.doc

X-ray repair cross complementing protein 1 in base excision repair.

Hanssen-Bauer A et al.

International Journal of Molecular Sciences, 2012

Genetic variability in DNA repair proteins in age-related macular degeneration.

Blasiak J et al.

International Journal of Molecular Sciences, 2012

Genetic variability in DNA repair and cell cycle control pathway genes and risk of smoking-related lung cancer.

Buch SC et al.

Molecular Carcinogenesis, 2012

Polymorphisms in human DNA repair genes and head and neck squamous cell carcinoma.

Khlifi R et al.

Journal of Genetics, 2012

Genetic polymorphisms and breast cancer risk: evidence from meta-analyses, pooled analyses, and genome-wide association studies.

Peng S et al.

Breast Cancer Research and Treatment, 2011

A functional -77T>C polymorphism in XRCC1 is associated with risk of breast cancer.

Liu L et al.

Breast Cancer Research and Treatment, 2011

Association of Arg194Trp, Arg280His and Arg399Gln polymorphisms in X-ray repair cross-complementing group 1 gene and risk of differentiated thyroid carcinoma in Iran.

Fard-Esfahani P et al.

Iranian Biomedical Journal, 2011

Smoking and selected DNA repair gene polymorphisms in controls: systematic review and meta-analysis.

Hodgson ME et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2010

No association between XRCC1 polymorphisms and survival in non-small-cell lung cancer patients treated with platinum-based chemotherapy.

Yuan P et al.

Cancer Biology & Therapy, 2010

Genetic variation in DNA repair genes and prostate cancer risk: results from a population-based study.

Agalliu I et al.

Cancer Causes & Control : Ccc, 2010

Genetic polymorphisms in DNA repair and damage response genes and late normal tissue complications of radiotherapy for breast cancer.

Chang-Claude J et al.

British Journal of Cancer, 2009

Association between polymorphisms in DNA base excision repair genes XRCC1, APE1, and ADPRT and differentiated thyroid carcinoma.

Chiang FY et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2008

Polymorphisms in DNA repair genes, smoking, and pancreatic adenocarcinoma risk.

McWilliams RR et al.

Cancer Research, 2008

Genetic polymorphism in bladder cancer.

Wu X et al.

Frontiers in Bioscience : a Journal and Virtual Library, 2007

Polymorphisms of DNA repair genes and risk of non-small cell lung cancer.

Zienolddiny S et al.

Carcinogenesis, 2006

Polymorphism in the DNA repair enzyme XRCC1: utility of current database and implications for human health risk assessment.

Ginsberg G et al.

Mutation Research, 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."