Varaico: Literature-Extracted Genetic Variants

Gene:ERCC5
Variant:p.K751Q
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ERCC5

NM_000123.4:p.K751Q

Associated Papers

The interplay between XPG-Asp1104His polymorphism and reproductive risk factors elevates risk of breast cancer in Tanzanian women: A multiple interaction analysis.

Adolf IC et al.

Cancer Medicine, 2023

Decoding Cancer Variants of Unknown Significance for Helicase-Nuclease-RPA Complexes Orchestrating DNA Repair During Transcription and Replication.

Tsutakawa SE et al.

Frontiers in Molecular Biosciences, 2021

34966786 (PubMed )
Supplement: Table3.XLSX › ERCC5

Predictive Value of Single Nucleotide Polymorphisms of ERCC1, XPA, XPC, XPD and XPG Genes, Involved in NER Mechanism in Patients with Advanced NSCLC Treated with Cisplatin and Gemcitabine.

Mlak R et al.

Pathology Oncology Research : Por, 2019

Different patterns of allelic imbalance in sporadic tumors and tumors associated with long-term exposure to gamma-radiation.

Litviakov NV et al.

Mutation Research. Genetic Toxicology and Environmental Mutagenesis, 2015

Associations of DNA-repair gene polymorphisms with a genetic susceptibility to ionizing radiation in residents of areas with high radon (222Rn) concentration.

Sinitsky MY et al.

International Journal of Radiation Biology, 2015

Pharmacogenetics of the DNA repair pathways in advanced non-small cell lung cancer patients treated with platinum-based chemotherapy.

Sullivan I et al.

Cancer Letters, 2014

Molecular epidemiology of DNA repair gene polymorphisms and head and neck cancer.

Wang M et al.

Journal of Biomedical Research, 2013

Novel XPG (ERCC5) mutations affect DNA repair and cell survival after ultraviolet but not oxidative stress.

Soltys DT et al.

Human Mutation, 2013

Major efficacy of trabectedin in 2 metastatic osteosarcoma patients with wild-type Asp1104 ERCC5 tumor status.

Gastaud L et al.

Onkologie, 2013

Association between the ERCC5 Asp1104His polymorphism and cancer risk: a meta-analysis.

Zhu ML et al.

Plos One, 2012

22815677 (PubMed )
Supplement: pone.0036293.s005.docx

Effect of occupational exposure to cytostatics and nucleotide excision repair polymorphism on chromosomal aberrations frequency.

Mušák L et al.

Interdisciplinary Toxicology, 2009

Polymorphisms in DNA repair genes and risk of non-Hodgkin's lymphoma in New South Wales, Australia.

Shen M et al.

Haematologica, 2007

Polymorphisms in XPD (Asp312Asn and Lys751Gln) genes, sunburn and arsenic-related skin lesions.

McCarty KM et al.

Carcinogenesis, 2007

Nucleotide excision repair as a marker for susceptibility to tobacco-related cancers: a review of molecular epidemiological studies.

Neumann AS et al.

Molecular Carcinogenesis, 2005

ERCC2 /XPD gene polymorphisms and lung cancer: a HuGE review.

Benhamou S et al.

American Journal of Epidemiology, 2005

ERCC2/XPD gene polymorphisms and cancer risk.

Benhamou S et al.

Mutagenesis, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."