Varaico: Literature-Extracted Genetic Variants

Gene:ERRFI1
Variant:p.Y395F
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ERRFI1

NM_018948.4:p.Y395F

Associated Papers

Functional loss of ERBB receptor feedback inhibitor 1 (MIG6) promotes glioblastoma tumorigenesis by aberrant activation of epidermal growth factor receptor (EGFR).

Yi SA et al.

Molecular Oncology, 2025

Mutations in Mig6 reduce inhibition of the epidermal growth factor receptor.

Hayashi SY et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2024

MIG6 Mediates Adaptive and Acquired Resistance to ALK/ROS1 Fusion Kinase Inhibition through EGFR Bypass Signaling.

Chen N et al.

Molecular Cancer Therapeutics, 2024

Structure and mechanism of activity-based inhibition of the EGF receptor by Mig6.

Park E et al.

Nature Structural & Molecular Biology, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."