Varaico: Literature-Extracted Genetic Variants

Gene:ESPL1
Variant:p.C2029S
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ESPL1

NM_012291.5:p.C2029S

Associated Papers

Substrate recognition by human separase.

Yu J et al.

Science Advances, 2025

Positively charged specificity site in cyclin B1 is essential for mitotic fidelity.

Heinzle C et al.

Nature Communications, 2025

Structural basis of human separase regulation by securin and CDK1-cyclin B1.

Yu J et al.

Nature, 2021

Polo kinase and separase regulate the mitotic licensing of centriole duplication in human cells.

Tsou MF et al.

Developmental Cell, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."