Varaico: Literature-Extracted Genetic Variants

Gene:ESR1
Variant:p.L349M
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ESR1

NM_000125.4:p.L349M

Associated Papers

Whole-exome mutational landscape of neuroendocrine carcinomas of the gallbladder.

Liu F et al.

Signal Transduction and Targeted Therapy, 2021

33563892 (PubMed )
Supplement: 41392_2020_412_MOESM19_ESM.xlsx › Supplementary_Table_S18

Reciprocal mutagenesis between human alpha(L349, M528) and rainbow trout (M317, I496) estrogen receptor residues demonstrates their importance in ligand binding and gene expression at different temperatures.

Matthews JB et al.

Molecular and Cellular Endocrinology, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."