Associated Papers
A PROSS-designed extensively mutated estrogen receptor α variant displays enhanced thermal stability while retaining native allosteric regulation and structure.
Kriegel M et al.
Scientific Reports, 2021
Structural and Molecular Mechanisms of Cytokine-Mediated Endocrine Resistance in Human Breast Cancer Cells.
Stender JD et al.
Molecular Cell, 2017
Estrogen and Estrogen Receptor-α-Mediated Transrepression of Bile Salt Export Pump.
Chen Y et al.
Molecular Endocrinology (baltimore, Md.), 2015
Structural basis for an unexpected mode of SERM-mediated ER antagonism.
Wu YL et al.
Molecular Cell, 2005
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