Varaico: Literature-Extracted Genetic Variants

Gene:ESR1
Variant:p.V376D
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ESR1

NM_000125.4:p.V376D

Associated Papers

The pure estrogen receptor antagonist ICI 182,780 promotes a novel interaction of estrogen receptor-alpha with the 3',5'-cyclic adenosine monophosphate response element-binding protein-binding protein/p300 coactivators.

Jaber BM et al.

Molecular Endocrinology (baltimore, Md.), 2006

The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation.

Lonard DM et al.

Molecular Cell, 2000

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."