Varaico: Literature-Extracted Genetic Variants

Gene:ESR1
Variant:p.G521R
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ESR1

NM_000125.4:p.G521R

Associated Papers

Forskolin Stimulates Estrogen Receptor (ER) α Transcriptional Activity and Protects ER from Degradation by Distinct Mechanisms.

Tsai HW et al.

International Journal of Endocrinology, 2022

18F-Fluoroestradiol PET Imaging of Activating Estrogen Receptor-α Mutations in Breast Cancer.

Kumar M et al.

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 2019

Uncovering the fine print of the CreERT2-LoxP system while generating a conditional knockout mouse model of Ssrp1 gene.

Sandlesh P et al.

Plos One, 2018

Low-level GATA2 overexpression promotes myeloid progenitor self-renewal and blocks lymphoid differentiation in mice.

Nandakumar SK et al.

Experimental Hematology, 2015

Interactions between the NR2B receptor and CaMKII modulate synaptic plasticity and spatial learning.

Zhou Y et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2007

Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice.

Li W et al.

Proceedings of the National Academy of Sciences of the United States of America, 2007

A functionally orthogonal estrogen receptor-based transcription switch specifically induced by a nonsteroid synthetic ligand.

Gallinari P et al.

Chemistry & Biology, 2005

ER-based double iCre fusion protein allows partial recombination in forebrain.

Casanova E et al.

Genesis (new York, N.y. : 2000), 2002

Long-term and tight control of gene expression in mouse skeletal muscle by a new hybrid human transcription factor.

Roscilli G et al.

Molecular Therapy : the Journal of the American Society of Gene Therapy, 2002

A tamoxifen-inducible chimeric Cre recombinase specifically effective in the fetal and adult mouse liver.

Tannour-Louet M et al.

Hepatology (baltimore, Md.), 2002

Three-dimensional models of estrogen receptor ligand binding domain complexes, based on related crystal structures and mutational and structure-activity relationship data.

Wurtz JM et al.

Journal of Medicinal Chemistry, 1998

Identification of amino acids in the hormone binding domain of the human estrogen receptor important in estrogen binding.

Ekena K et al.

The Journal of Biological Chemistry, 1996

Analysis of mechanisms that determine dominant negative estrogen receptor effectiveness.

Schodin DJ et al.

The Journal of Biological Chemistry, 1995

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."