Varaico: Literature-Extracted Genetic Variants

Gene:ESR1
Variant:p.G521A
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ESR1

NM_000125.4:p.G521A

Associated Papers

A human estrogen receptor (ER)alpha mutation with differential responsiveness to nonsteroidal ligands: novel approaches for studying mechanism of ER action.

Paulmurugan R et al.

Molecular Endocrinology (baltimore, Md.), 2008

Three-dimensional models of estrogen receptor ligand binding domain complexes, based on related crystal structures and mutational and structure-activity relationship data.

Wurtz JM et al.

Journal of Medicinal Chemistry, 1998

Homology model for the ligand-binding domain of the human estrogen receptor.

Maalouf GJ et al.

Journal of Biomolecular Structure & Dynamics, 1998

Different residues of the human estrogen receptor are involved in the recognition of structurally diverse estrogens and antiestrogens.

Ekena K et al.

The Journal of Biological Chemistry, 1997

Identification of amino acids in the hormone binding domain of the human estrogen receptor important in estrogen binding.

Ekena K et al.

The Journal of Biological Chemistry, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."