Varaico: Literature-Extracted Genetic Variants

Gene:ESR1
Variant:p.L536I
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ESR1

NM_000125.4:p.L536I

Associated Papers

Evaluation of endocrine resistance using ESR1 genotyping of circulating tumor cells and plasma DNA.

Sundaresan TK et al.

Breast Cancer Research and Treatment, 2021

Mutation of Leu-536 in human estrogen receptor-alpha alters the coupling between ligand binding, transcription activation, and receptor conformation.

Zhao C et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."