Associated Papers
Cadmium activation of wild-type and constitutively active estrogen receptor alpha.
Psaltis JB et al.
Frontiers in Endocrinology, 2024
Forskolin Stimulates Estrogen Receptor (ER) α Transcriptional Activity and Protects ER from Degradation by Distinct Mechanisms.
Tsai HW et al.
International Journal of Endocrinology, 2022
Estrogen receptor mutations found in breast cancer metastases integrated with the molecular pharmacology of selective ER modulators.
Jordan VC et al.
Journal of the National Cancer Institute, 2015
Emergence of constitutively active estrogen receptor-α mutations in pretreated advanced estrogen receptor-positive breast cancer.
Jeselsohn R et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2014
D538G mutation in estrogen receptor-α: A novel mechanism for acquired endocrine resistance in breast cancer.
Merenbakh-Lamin K et al.
Cancer Research, 2013
ESR1 ligand-binding domain mutations in hormone-resistant breast cancer.
Toy W et al.
Nature Genetics, 2013
Agonist-like SERM effects on ERalpha-mediated repression of MMP1 promoter activity predict in vivo effects on bone and uterus.
Scafonas A et al.
The Journal of Steroid Biochemistry and Molecular Biology, 2008
Estrogenic effects of resveratrol in breast cancer cells expressing mutant and wild-type estrogen receptors: role of AF-1 and AF-2.
Gehm BD et al.
The Journal of Steroid Biochemistry and Molecular Biology, 2004
Modulation of estrogen receptor alpha function and stability by tamoxifen and a critical amino acid (Asp-538) in helix 12.
Pearce ST et al.
The Journal of Biological Chemistry, 2003
Structural regions of ERalpha critical for synergistic transcriptional responses contain co-factor interacting surfaces.
Sathya G et al.
Molecular and Cellular Endocrinology, 2002
Fusion estrogen receptor proteins: toward the development of receptor-based agonists and antagonists.
Muyan M et al.
Molecular and Cellular Endocrinology, 2001
Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor alpha complex.
Liu H et al.
Cancer Research, 2001
Allosteric silencing of activating function 1 in the 4-hydroxytamoxifen estrogen receptor complex is induced by substituting glycine for aspartate at amino acid 351.
MacGregor Schafer J et al.
Cancer Research, 2000
The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation.
Lonard DM et al.
Molecular Cell, 2000
Three-dimensional models of estrogen receptor ligand binding domain complexes, based on related crystal structures and mutational and structure-activity relationship data.
Wurtz JM et al.
Journal of Medicinal Chemistry, 1998