Associated Papers
Cadmium activation of wild-type and constitutively active estrogen receptor alpha.
Psaltis JB et al.
Frontiers in Endocrinology, 2024
NGS-based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment.
Sánchez-Herrero E et al.
Molecular Oncology, 2021
Molecular characterisation of aromatase inhibitor-resistant advanced breast cancer: the phenotypic effect of ESR1 mutations.
Lopez-Knowles E et al.
British Journal of Cancer, 2019
Molecular evaluation of PIK3CA gene mutation in breast cancer: determination of frequency, distribution pattern and its association with clinicopathological findings in Indian patients.
Ahmad F et al.
Medical Oncology (northwood, London, England), 2016
PIK3CA mutation impact on survival in breast cancer patients and in ERα, PR and ERBB2-based subgroups.
Cizkova M et al.
Breast Cancer Research : Bcr, 2012
Agonist-like SERM effects on ERalpha-mediated repression of MMP1 promoter activity predict in vivo effects on bone and uterus.
Scafonas A et al.
The Journal of Steroid Biochemistry and Molecular Biology, 2008
Mutational hotspot in exon 20 of PIK3CA in breast cancer among Singapore Chinese.
Liang X et al.
Cancer Biology & Therapy, 2006
Frequent mutation of the PIK3CA gene in ovarian and breast cancers.
Levine DA et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2005
Estrogenic effects of resveratrol in breast cancer cells expressing mutant and wild-type estrogen receptors: role of AF-1 and AF-2.
Gehm BD et al.
The Journal of Steroid Biochemistry and Molecular Biology, 2004
Modulation of estrogen receptor alpha function and stability by tamoxifen and a critical amino acid (Asp-538) in helix 12.
Pearce ST et al.
The Journal of Biological Chemistry, 2003
Structural regions of ERalpha critical for synergistic transcriptional responses contain co-factor interacting surfaces.
Sathya G et al.
Molecular and Cellular Endocrinology, 2002
Fusion estrogen receptor proteins: toward the development of receptor-based agonists and antagonists.
Muyan M et al.
Molecular and Cellular Endocrinology, 2001
Silencing and reactivation of the selective estrogen receptor modulator-estrogen receptor alpha complex.
Liu H et al.
Cancer Research, 2001
Allosteric silencing of activating function 1 in the 4-hydroxytamoxifen estrogen receptor complex is induced by substituting glycine for aspartate at amino acid 351.
MacGregor Schafer J et al.
Cancer Research, 2000
The 26S proteasome is required for estrogen receptor-alpha and coactivator turnover and for efficient estrogen receptor-alpha transactivation.
Lonard DM et al.
Molecular Cell, 2000
Human estrogen receptor ligand activity inversion mutants: receptors that interpret antiestrogens as estrogens and estrogens as antiestrogens and discriminate among different antiestrogens.
Montano MM et al.
Molecular Endocrinology (baltimore, Md.), 1996