Varaico: Literature-Extracted Genetic Variants

Gene:ETV6
Variant:p.K99R
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ETV6

NM_001987.5:p.K99R

Associated Papers

RUNX-mediated growth arrest and senescence are attenuated by diverse mechanisms in cells expressing RUNX1 fusion oncoproteins.

Anderson G et al.

Journal of Cellular Biochemistry, 2018

Mutation of the salt bridge-forming residues in the ETV6-SAM domain interface blocks ETV6-NTRK3-induced cellular transformation.

Cetinbas N et al.

The Journal of Biological Chemistry, 2013

TEL, a putative tumor suppressor, induces apoptosis and represses transcription of Bcl-XL.

Irvin BJ et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."