Associated Papers
Importins recognize the winged-helix fold of ETS transcription factors to mediate nuclear import.
McConville BM et al.
Biorxiv : the Preprint Server for Biology, 2026
Clonal architecture of FLT3-ITD and acquired 13q uniparental disomy define prognostic heterogeneity and therapeutic vulnerabilities in acute myeloid leukemia.
Lai A et al.
Neoplasia (new York, N.y.), 2025
A germline ETV6 mutation disrupts hematopoiesis via de novo creation of a nuclear export signal.
McConville M et al.
Science Advances, 2025
Comprehensive genetic analysis for identification of monogenic disorders and selection of appropriate treatments in pediatric patients with persistent thrombocytopenia.
Sato D et al.
Pediatric Hematology and Oncology, 2024
Enigmatic missense mutations can cause disease via creation of de novo nuclear export signals.
McConville BM et al.
Biorxiv : the Preprint Server for Biology, 2024
Unveiling the signaling network of FLT3-ITD AML improves drug sensitivity prediction.
Latini S et al.
Elife, 2024
In a multi-institutional cohort of myeloid sarcomas, NFE2 mutation prevalence is lower than previously reported.
Anekpuritanang T et al.
Blood Advances, 2021
Functional analysis of germline ETV6 W380R mutation causing inherited thrombocytopenia and secondary acute lymphoblastic leukemia or essential thrombocythemia.
Kozubik KS et al.
Platelets, 2021
Germline pathogenic variants in transcription factors predisposing to pediatric acute myeloid leukemia: results from the French ELAM02 trial.
Fenwarth L et al.
Haematologica, 2021
Invariant patterns of clonal succession determine specific clinical features of myelodysplastic syndromes.
Nagata Y et al.
Nature Communications, 2019
Predisposition to childhood acute lymphoblastic leukemia caused by a constitutional translocation disrupting ETV6.
Järviaho T et al.
Blood Advances, 2019
ETV6-related thrombocytopenia and leukemia predisposition.
Di Paola J et al.
Blood, 2019
Detection of a new heterozygous germline ETV6 mutation in a case with hyperdiploid acute lymphoblastic leukemia.
Duployez N et al.
European Journal of Haematology, 2018
Germline ETV6 mutations and predisposition to hematological malignancies.
Feurstein S et al.
International Journal of Hematology, 2017
ETV6 in hematopoiesis and leukemia predisposition.
Hock H et al.
Seminars in Hematology, 2017
Clinical and pathogenic features of ETV6-related thrombocytopenia with predisposition to acute lymphoblastic leukemia.
Melazzini F et al.
Haematologica, 2016
ETV6 mutations define a new cancer predisposition syndrome.
Kirkpatrick G et al.
Oncotarget, 2015
Germline ETV6 Mutations Confer Susceptibility to Acute Lymphoblastic Leukemia and Thrombocytopenia.
Topka S et al.
Plos Genetics, 2015
Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia.
Noetzli L et al.
Nature Genetics, 2015
Functional consequences of somatic mutations in cancer using protein pocket-based prioritization approach.
Vuong H et al.
Genome Medicine, 2014
alpha-1-Antichymotrypsin gene A1252G variant (ACT Isehara-1) is associated with a lacunar type of ischemic cerebrovascular disease.
Tachikawa H et al.
Journal of Human Genetics, 2001