Varaico: Literature-Extracted Genetic Variants

Gene:EXO1
Variant:p.E150D
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EXO1

NM_130398.4:p.E150D

Associated Papers

Mitochondrial superoxide dismutase Sod2 suppresses nuclear genome instability during oxidative stress.

Gupta SV et al.

Genetics, 2023

Exo1 phosphorylation inhibits exonuclease activity and prevents fork collapse in rad53 mutants independently of the 14-3-3 proteins.

Morafraile EC et al.

Nucleic Acids Research, 2020

Exo1 phosphorylation status controls the hydroxyurea sensitivity of cells lacking the Pol32 subunit of DNA polymerases delta and zeta.

Doerfler L et al.

Dna Repair, 2014

Exonuclease 1 (Exo1) is required for activating response to S(N)1 DNA methylating agents.

Izumchenko E et al.

Dna Repair, 2012

Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks.

Segurado M et al.

Genes & Development, 2008

A mutation in EXO1 defines separable roles in DNA mismatch repair and post-replication repair.

Tran PT et al.

Dna Repair, 2007

Characterization of nuclease-dependent functions of Exo1p in Saccharomyces cerevisiae.

Tran PT et al.

Dna Repair, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."