Varaico: Literature-Extracted Genetic Variants

Gene:EXO1
Variant:p.P757L
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EXO1

NM_130398.4:p.P757L

Associated Papers

The pharmacogenomic landscape in the Chinese: An analytics of pharmacogenetic variants in 206,640 individuals.

Wang LY et al.

Innovation (cambridge (mass.)), 2025

39991480 (PubMed )
Supplement: mmc5.xlsx › Sheet1

Novel NARS2 variants in a patient with early-onset status epilepticus: case study and literature review.

Yang N et al.

Bmc Pediatrics, 2024

38310242 (PubMed )
Supplement: 12887_2024_4553_MOESM1_ESM.xlsx › trio.hg38.filter

ATR inhibition using gartisertib enhances cell death and synergises with temozolomide and radiation in patient-derived glioblastoma cell lines.

Lozinski M et al.

Oncotarget, 2024

38227740 (PubMed )
Supplement: oncotarget-15-28551-s001.pdf

Genomic Landscape of Normal and Breast Cancer Tissues in a Hungarian Pilot Cohort.

Pipek O et al.

International Journal of Molecular Sciences, 2023

37239898 (PubMed )
Supplement: ijms-24-08553-s001.zip › Supp_Fig_1_new.pdf

Association study of candidate DNA-repair gene variants and acute graft versus host disease in pediatric patients receiving allogeneic hematopoietic stem-cell transplantation.

Uppugunduri CRS et al.

The Pharmacogenomics Journal, 2022

A systematic genome-wide mapping of oncogenic mutation selection during CRISPR-Cas9 genome editing.

Sinha S et al.

Nature Communications, 2021

34764240 (PubMed )
Supplement: 41467_2021_26788_MOESM14_ESM.zip › Source_Data › Source_Data_Figure_1-6.xlsx › Figure_6F

Somatic mutations in the DNA repairome in prostate cancers in African Americans and Caucasians.

Yadav S et al.

Oncogene, 2020

32300177 (PubMed )
Supplement: 41388_2020_1280_MOESM3_ESM.xlsx › Main_Sheet_

Polymorphisms in DNA mismatch repair pathway genes predict toxicity and response to cisplatin chemoradiation in head and neck squamous cell carcinoma patients.

Nogueira GAS et al.

Oncotarget, 2018

XRCC3 Thr241Met and TYMS variable number tandem repeat polymorphisms are associated with time-to-metastasis in colorectal cancer.

He Y et al.

Plos One, 2018

Significant association of the EXO1 rs851797 polymorphism with clinical outcome of ovarian cancer.

Shi T et al.

Oncotargets and Therapy, 2017

Impact of Polymorphic Variations of Gemcitabine Metabolism, DNA Damage Repair, and Drug-Resistance Genes on the Effect of High-Dose Chemotherapy for Relapsed or Refractory Lymphoid Malignancies.

Shinozuka K et al.

Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation, 2016

Association of DNA repair gene polymorphisms with response to cisplatin-based concurrent chemoradiotherapy in patients with cervical carcinoma.

Liu JH et al.

Dna Repair, 2016

Variation analysis of EXO1 gene in Chinese patients with premature ovarian failure.

Su S et al.

Reproductive Biomedicine Online, 2016

Association between three exonuclease 1 polymorphisms and cancer risks: a meta-analysis.

Chen ZY et al.

Oncotargets and Therapy, 2016

Identification of HPV integration and gene mutation in HeLa cell line by integrated analysis of RNA-Seq and MS/MS data.

Sun H et al.

Journal of Proteome Research, 2015

25698088 (PubMed )
Supplement: pr500944c_si_009.xlsx › SNV

Integrated mRNA and microRNA transcriptome sequencing characterizes sequence variants and mRNA-microRNA regulatory network in nasopharyngeal carcinoma model systems.

Szeto CY et al.

Febs Open Bio, 2014

24490137 (PubMed )
Supplement: mmc5.xlsx › coding

MTHFR Glu429Ala and ERCC5 His46His polymorphisms are associated with prognosis in colorectal cancer patients: analysis of two independent cohorts from Newfoundland.

Negandhi AA et al.

Plos One, 2013

The joint effect of smoking and hOGG1 genotype on oral cancer in Taiwan.

Tsai CW et al.

Anticancer Research, 2012

A single nucleotide polymorphism in EXO1 gene is associated with cervical cancer susceptibility in Chinese patients.

Luo X et al.

International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society, 2012

Genetic polymorphisms in DNA repair and oxidative stress pathways associated with malignant melanoma susceptibility.

Ibarrola-Villava M et al.

European Journal of Cancer (oxford, England : 1990), 2011

Interaction of CCND1 genotype and smoking habit in Taiwan lung cancer patients.

Hsia TC et al.

Anticancer Research, 2011

Impact of EXO1 polymorphism in susceptibility to colorectal cancer.

Haghighi MM et al.

Genetic Testing and Molecular Biomarkers, 2010

Association of genetic polymorphisms of EXO1 gene with risk of breast cancer in Taiwan.

Wang HC et al.

Anticancer Research, 2009

Interaction of Exo1 genotypes and smoking habit in oral cancer in Taiwan.

Tsai MH et al.

Oral Oncology, 2009

Lung cancer susceptibility and genetic polymorphisms of Exo1 gene in Taiwan.

Hsu NY et al.

Anticancer Research, 2009

Influence of cancer-related gene polymorphisms on clinicopathological features in colorectal cancer.

Yoshiya G et al.

Journal of Gastroenterology and Hepatology, 2008

Nuclear localization of human DNA mismatch repair protein exonuclease 1 (hEXO1).

Knudsen NØ et al.

Nucleic Acids Research, 2007

Polymorphisms of DNA repair genes and risk of non-small cell lung cancer.

Zienolddiny S et al.

Carcinogenesis, 2006

Single nucleotide polymorphisms in the EXO1 gene and risk of colorectal cancer in a Japanese population.

Yamamoto H et al.

Carcinogenesis, 2005

Germline mutations of EXO1 gene in patients with hereditary nonpolyposis colorectal cancer (HNPCC) and atypical HNPCC forms.

Wu Y et al.

Gastroenterology, 2001

Sporadic colorectal cancer and individual susceptibility: a review of the association studies investigating the role of DNA repair genetic polymorphisms.

Naccarati A et al.

Mutation Research, 0

Interaction of methylenetetrahydrofolate reductase genotype and smoking habit in Taiwanese lung cancer patients.

Liu CS et al.

Cancer Genomics & Proteomics, 0

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