Varaico: Literature-Extracted Genetic Variants

Gene:EXOSC10
Variant:p.D313N
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EXOSC10

NM_001001998.3:p.D313N

Associated Papers

Regulation of the conserved 3'-5' exoribonuclease EXOSC10/Rrp6 during cell division, development and cancer.

Stuparević I et al.

Biological Reviews of the Cambridge Philosophical Society, 2021

The RNA exosome complex degrades expanded hexanucleotide repeat RNA in C9orf72 FTLD/ALS.

Kawabe Y et al.

The Embo Journal, 2020

Helicase-Dependent RNA Decay Illuminated by a Cryo-EM Structure of a Human Nuclear RNA Exosome-MTR4 Complex.

Weick EM et al.

Cell, 2018

DGCR8 Acts as an Adaptor for the Exosome Complex to Degrade Double-Stranded Structured RNAs.

Macias S et al.

Molecular Cell, 2015

RRP6 from Trypanosoma brucei: crystal structure of the catalytic domain, association with EAP3 and activity towards structured and non-structured RNA substrates.

Barbosa RL et al.

Plos One, 2014

Activities of human RRP6 and structure of the human RRP6 catalytic domain.

Januszyk K et al.

Rna (new York, N.y.), 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."