Varaico: Literature-Extracted Genetic Variants

Gene:EZH2
Variant:p.I146T
Back to variants list

EZH2

NM_004456.5:p.I146T

Associated Papers

Dominant-negative effects of Weaver syndrome-associated EZH2 variants.

Deevy O et al.

Genes & Development, 2025

40846643 (PubMed )
Supplement: Supplemental_Data.docx

Whole Exome Sequencing of Intermediate-Risk Acute Myeloid Leukemia without Recurrent Genetic Abnormalities Offers Deeper Insights into New Diagnostic Classifications.

Guijarro F et al.

International Journal of Molecular Sciences, 2024

39201354 (PubMed )
Supplement: ijms-25-08669-s001.zip › ijms-3087068-supplementary › Supplementary_Tables_S1-S5.xlsx › Table_S1

Polycomb Alterations in Acute Myeloid Leukaemia: From Structure to Function.

Bhattacharyya T et al.

Cancers, 2023

Comprehensive Analysis of Acquired Genetic Variants and Their Prognostic Impact in Systemic Mastocytosis.

González-López O et al.

Cancers, 2022

Analysis of nonleukemic cellular subcompartments reconstructs clonal evolution of acute myeloid leukemia and identifies therapy-resistant preleukemic clones.

Saeed BR et al.

International Journal of Cancer, 2021

Leukemia Cell Lines: In Vitro Models for the Study of Chronic Neutrophilic Leukemia.

Drexler HG et al.

Current Oncology (toronto, Ont.), 2021

Activating somatic and germline TERT promoter variants in myeloid malignancies.

Nofrini V et al.

Leukemia, 2021

EZH2-activating mutation: no reliable indicator for efficacy of methyltransferase inhibitors.

Quentmeier H et al.

Leukemia & Lymphoma, 2020

EZH2 mutations and impact on clinical outcome: an analysis in 1,604 patients with newly diagnosed acute myeloid leukemia.

Stasik S et al.

Haematologica, 2020

Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential.

Wong TN et al.

Nature Communications, 2018

29386642 (PubMed )
Supplement: 41467_2018_2858_MOESM8_ESM.xlsx › TAML-TMDS

Mutations driving CLL and their evolution in progression and relapse.

Landau DA et al.

Nature, 2015

26466571 (PubMed )
Supplement: NIHMS715090-supplement-Supplementary_Table_10.xlsx › CCF_DP_clustering
Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."