Associated Papers
Activated ezrin controls MISP levels to ensure correct NuMA polarization and spindle orientation.
Kschonsak YT et al.
Journal of Cell Science, 2018
Activation of moesin, a protein that links actin cytoskeleton to the plasma membrane, occurs by phosphatidylinositol 4,5-bisphosphate (PIP2) binding sequentially to two sites and releasing an autoinhibitory linker.
Ben-Aissa K et al.
The Journal of Biological Chemistry, 2012
Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin.
Fievet BT et al.
The Journal of Cell Biology, 2004
Mutagenesis of the phosphatidylinositol 4,5-bisphosphate (PIP(2)) binding site in the NH(2)-terminal domain of ezrin correlates with its altered cellular distribution.
Barret C et al.
The Journal of Cell Biology, 2000
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