Varaico: Literature-Extracted Genetic Variants

Gene:F11
Variant:p.C321S
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F11

NM_000128.4:p.C321S

Associated Papers

Factor XI homodimer structure is essential for normal proteolytic activation by factor XIIa, thrombin, and factor XIa.

Wu W et al.

The Journal of Biological Chemistry, 2008

Dimer dissociation and unfolding mechanism of coagulation factor XI apple 4 domain: spectroscopic and mutational analysis.

Riley PW et al.

Journal of Molecular Biology, 2007

Factor XIa dimer in the activation of factor IX.

Sinha D et al.

Biochemistry, 2005

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."