Varaico: Literature-Extracted Genetic Variants

Gene:F12
Variant:p.K27M
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F12

NM_000505.4:p.K27M

Associated Papers

Individualized patient tumor organoids faithfully preserve human brain tumor ecosystems and predict patient response to therapy.

Peng T et al.

Cell Stem Cell, 2025

3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma.

Okonechnikov K et al.

Nature Communications, 2023

Epigenome Programming by H3.3K27M Mutation Creates a Dependence of Pediatric Glioma on SMARCA4.

Mo Y et al.

Cancer Discovery, 2022

Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas.

Harpaz N et al.

Molecular Cell, 2022

Current Murine Models and New Developments in H3K27M Diffuse Midline Gliomas.

Welby JP et al.

Frontiers in Oncology, 2019

30873381 (PubMed )
Supplement: Data_Sheet_1.docx

Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma.

Huang TY et al.

Acta Neuropathologica Communications, 2017

Ofd1, a human disease gene, regulates the length and distal structure of centrioles.

Singla V et al.

Developmental Cell, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."