Associated Papers
Thrombomodulin Arg403Lys mutation impairs protein C activation and increases thrombosis risk.
Lai Z et al.
Thrombosis Research, 2025
Inherited thrombophilia in a Han Chinese family caused by prothrombin Ile441Met mutation.
Wen SY et al.
Research and Practice in Thrombosis and Haemostasis, 2025
Multigene panel for thrombophilia testing in venous thromboembolism.
Verstraete A et al.
Journal of Thrombosis and Haemostasis : Jth, 2025
Assessment of a next generation sequencing gene panel strategy in 133 patients with negative thrombophilia screening.
Suchon P et al.
Journal of Thrombosis and Haemostasis : Jth, 2025
Heterozygous Prothrombin Mutation-Associated Thrombophilia.
Wu X et al.
Thrombosis and Haemostasis, 2025
Whole-Exome Sequencing in a Family with an Unexplained Tendency for Venous Thromboembolism: Multicomponent Prediction of Low-Frequency Variant Deleteriousness and of Individual Protein Interaction.
Lunghi B et al.
International Journal of Molecular Sciences, 2023
Venous thromboembolism is caused by prothrombin p.Arg541Trp mutation in Japanese individuals.
Yamamoto J et al.
Human Genome Variation, 2021
Linkage analysis combined with whole-exome sequencing identifies a novel prothrombin (F2) gene mutation in a Dutch Caucasian family with unexplained thrombosis.
Mulder R et al.
Haematologica, 2020
Prothrombin Arg541Trp Mutation Leads to Defective PC (Protein C) Pathway Activation and Constitutes a Novel Genetic Risk Factor for Venous Thrombosis.
Wu X et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2020
A Novel Heterozygous Variant in F2 Gene in a Chinese Patient With Coronary Thrombosis and Acute Myocardial Infarction Leads to Antithrombin Resistance.
Tang Y et al.
Frontiers in Genetics, 2020
In vitro exploration of latent prothrombin mutants conveying antithrombin resistance.
Tamura S et al.
Thrombosis Research, 2017
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