Associated Papers
The Effects of Heparin Binding and Arg596 Mutations on the Conformation of Thrombin-Antithrombin Michaelis Complex, Revealed by Enhanced Sampling Molecular Dynamics Simulations.
Balogh G et al.
International Journal of Molecular Sciences, 2025
Venous thromboembolism laboratory testing (factor V Leiden and factor II c.∗97G>A), 2025 revision: A technical standard of the American College of Medical Genetics and Genomics (ACMG).
Kang BE et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2025
Inherited thrombophilia in a Han Chinese family caused by prothrombin Ile441Met mutation.
Wen SY et al.
Research and Practice in Thrombosis and Haemostasis, 2025
Comprehensive review of thrombophilia: pathophysiology, prevalence, risk factors, and molecular diagnosis.
Altwayan R et al.
Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine, 2025
Systemic thrombosis with prothrombin Belgrade mutation in a Chinese patient: A case report.
Wu YF et al.
World Journal of Clinical Cases, 2025
Assessment of a next generation sequencing gene panel strategy in 133 patients with negative thrombophilia screening.
Suchon P et al.
Journal of Thrombosis and Haemostasis : Jth, 2025
Identification of Prothrombin Belgrade Variant in a Mexican-American Family with Recurrent Deep Vein Thrombosis.
Moura Coelho da Silva É et al.
Th Open : Companion Journal to Thrombosis and Haemostasis, 2025
Evaluation of prothrombotic risk of two PROC hotspot mutations (Arg189Trp and Lys193del) in Chinese population: a retrospective study.
Li L et al.
Thrombosis Journal, 2023
Three Cases of Unprovoked Venous Thromboembolism with Prothrombin p.Arg596Gln Variant and a Literature Review of Antithrombin Resistance.
Tsuji A et al.
Internal Medicine (tokyo, Japan), 2023
Evolving Knowledge on Primary and Secondary Prevention of Venous Thromboembolism in Carriers of Hereditary Thrombophilia: A Narrative Review.
Campello E et al.
Seminars in Thrombosis and Hemostasis, 2022
Clinical guidance for peripartum management of patients with hereditary thrombophilia.
Kobayashi T et al.
The Journal of Obstetrics and Gynaecology Research, 2021
Rare Defects: Looking at the Dark Face of the Thrombosis.
D'Andrea G et al.
International Journal of Environmental Research and Public Health, 2021
Genetic risk factors for venous thromboembolism.
Zöller B et al.
Expert Review of Hematology, 2020
A Novel Heterozygous Variant in F2 Gene in a Chinese Patient With Coronary Thrombosis and Acute Myocardial Infarction Leads to Antithrombin Resistance.
Tang Y et al.
Frontiers in Genetics, 2020
New data on FII, FV, FIX and thrombomodulin defects: blood keeps clotting in normal and in peculiar ways.
Girolami A et al.
Hematology (amsterdam, Netherlands), 2019
Thrombophilia, risk factors and prevention.
Campello E et al.
Expert Review of Hematology, 2019
A paradoxical thrombogenic mutation in factor II at the target site of arthropod bleeding toxin.
Takenouchi T et al.
European Journal of Medical Genetics, 2019
Venous thromboembolism laboratory testing (factor V Leiden and factor II c.*97G>A), 2018 update: a technical standard of the American College of Medical Genetics and Genomics (ACMG).
Zhang S et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2018
Vitamin K-Dependent Coagulation Factors That May be Responsible for Both Bleeding and Thrombosis (FII, FVII, and FIX).
Girolami A et al.
Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/hemostasis, 2018
Prothrombin: Another Clotting Factor After FV That Is Involved Both in Bleeding and Thrombosis.
Girolami A et al.
Clinical and Applied Thrombosis/hemostasis : Official Journal of the International Academy of Clinical and Applied Thrombosis/hemostasis, 2018
Screening and functional exploration of prothrombin Arg596 related mutations in Chinese venous thromboembolism patients.
Wu X et al.
Journal of Clinical Pathology, 2018
Familial pulmonary thromboembolism with a prothrombin mutation and antithrombin resistance.
Yoshida R et al.
Journal of Cardiology Cases, 2018
Congenital prothrombin defects: they are not only associated with bleeding but also with thrombosis: a new classification is needed.
Girolami A et al.
Hematology (amsterdam, Netherlands), 2018
In vitro exploration of latent prothrombin mutants conveying antithrombin resistance.
Tamura S et al.
Thrombosis Research, 2017
New clotting disorders that cast new light on blood coagulation and may play a role in clinical practice.
Girolami A et al.
Journal of Thrombosis and Thrombolysis, 2017
Clinical and biochemical characterization of the prothrombin Belgrade mutation in a large Serbian pedigree: new insights into the antithrombin resistance mechanism.
Miljic P et al.
Journal of Thrombosis and Haemostasis : Jth, 2017
Genetic Risk Factors in Venous Thromboembolism.
Hotoleanu C
Advances in Experimental Medicine and Biology, 2017
Missense mutations in the gene encoding prothrombin corresponding to Arg596 cause antithrombin resistance and thrombomodulin resistance.
Takagi Y et al.
Thrombosis and Haemostasis, 2016
New Prothrombin Mutation (Arg596Trp, Prothrombin Padua 2) Associated With Venous Thromboembolism.
Bulato C et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2016
The first case of antithrombin-resistant prothrombin Belgrade mutation in Japanese.
Kishimoto M et al.
Annals of Hematology, 2016
[Antithrombin resistance: a new mechanism of inherited thrombophilia].
Kojima T et al.
[rinsho Ketsueki] the Japanese Journal of Clinical Hematology, 2015
High prophylactic LMWH dose successfully suppressed hemostatic activation in pregnant woman with a new prothrombin c.1787G>A mutation.
Kovac M et al.
Thrombosis Research, 2015
Antithrombin-resistant prothrombin Yukuhashi mutation also causes thrombomodulin resistance in fibrinogen clotting but not in protein C activation.
Takagi Y et al.
Thrombosis Research, 2014
[Discovery and prospects of a novel thrombophilia: antithrombin resistance].
Takagi Y et al.
Nihon Rinsho. Japanese Journal of Clinical Medicine, 2014
Development of a new laboratory test to evaluate antithrombin resistance in plasma.
Murata M et al.
Thrombosis Research, 2014
A novel prothrombin mutation in two families with prominent thrombophilia--the first cases of antithrombin resistance in a Caucasian population.
Djordjevic V et al.
Journal of Thrombosis and Haemostasis : Jth, 2013
Prothrombin mutation conveying antithrombin resistance.
Lotta LA et al.
The New England Journal of Medicine, 2012
Prothrombin mutation conveying antithrombin resistance.
Simioni P et al.
The New England Journal of Medicine, 2012
Thrombosis from a prothrombin mutation conveying antithrombin resistance.
Miyawaki Y et al.
The New England Journal of Medicine, 2012