Associated Papers
Toward non-factor therapy in hemophilia: an antithrombin insensitive Gla-domainless factor Xa as tissue factor pathway inhibitor bait.
Dagher MC et al.
Research and Practice in Thrombosis and Haemostasis, 2023
Characterization of the enzymatic activity of the serine protease domain of Factor VII activating protease (FSAP).
Nielsen NV et al.
Scientific Reports, 2019
Dual functionality of β-tryptase protomers as both proteases and cofactors in the active tetramer.
Maun HR et al.
The Journal of Biological Chemistry, 2018
Rendering factor Xa zymogen-like as a therapeutic strategy to treat bleeding.
Thalji NK et al.
Current Opinion in Hematology, 2017
Thermodynamic signatures in macromolecular interactions involving conformational flexibility.
Menzel A et al.
Biological Chemistry, 2014
Crystal structure of the prothrombinase complex from the venom of Pseudonaja textilis.
Lechtenberg BC et al.
Blood, 2013
An anticoagulant RNA aptamer that inhibits proteinase-cofactor interactions within prothrombinase.
Buddai SK et al.
The Journal of Biological Chemistry, 2010
The conformational switch from the factor X zymogen to protease state mediates exosite expression and prothrombinase assembly.
Toso R et al.
The Journal of Biological Chemistry, 2008
Identification of a basic region on tissue factor that interacts with the first epidermal growth factor-like domain of factor X.
Manithody C et al.
Biochemistry, 2007
Analysis of the factor VIIa binding site on human tissue factor: effects of tissue factor mutations on the kinetics and thermodynamics of binding.
Kelley RF et al.
Biochemistry, 1995
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