Associated Papers
Factor V variants in bleeding and thrombosis.
Mohapatra AK et al.
Research and Practice in Thrombosis and Haemostasis, 2024
Rare inherited coagulation and fibrinolytic defects that challenge diagnostic laboratories.
Mathews N et al.
International Journal of Laboratory Hematology, 2023
A hydrophobic patch (PLVIVG; 1481-1486) in the B-domain of factor V-short is crucial for its synergistic TFPIα-cofactor activity with protein S and for the formation of the FXa-inhibitory complex comprising FV-short, TFPIα, and protein S.
Dahlbäck B et al.
Journal of Thrombosis and Haemostasis : Jth, 2022
The preAR2 region (1458-1492) in factor V-Short is crucial for the synergistic TFPIα-cofactor activity with protein S and the assembly of a trimolecular factor Xa-inhibitory complex comprising FV-Short, protein S, and TFPIα.
Dahlbäck B et al.
Journal of Thrombosis and Haemostasis : Jth, 2022
Natural anticoagulants: A missing link in mild to moderate bleeding tendencies.
Mehic D et al.
Haemophilia : the Official Journal of the World Federation of Hemophilia, 2021
F5-Atlanta: A novel mutation in F5 associated with enhanced East Texas splicing and FV-short production.
Zimowski KL et al.
Journal of Thrombosis and Haemostasis : Jth, 2021
Elevated levels of tissue factor pathway inhibitor in patients with mild to moderate bleeding tendency.
Mehic D et al.
Blood Advances, 2021
Investigation of patients with unclassified bleeding disorder and abnormal thrombin generation for physiological coagulation inhibitors reveals multiple abnormalities and a subset of patients with increased tissue factor pathway inhibitor activity.
MacDonald S et al.
International Journal of Laboratory Hematology, 2020
A novel mutation in the F5 gene (factor V Amsterdam) associated with bleeding independent of factor V procoagulant function.
Cunha ML et al.
Blood, 2015
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