Varaico: Literature-Extracted Genetic Variants

Gene:F7
Variant:p.G134V
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F7

NM_019616.4:p.G134V

Associated Papers

Coagulation Factor VII Deficiency: A Review of the Clinical Implications and Approaches to Replacement Therapy and Prophylaxis.

Cohan N et al.

Pediatric Blood & Cancer, 2025

Molecular Genetic Analysis of Russian Patients with Coagulation Factor FVII Deficiency.

Pshenichnikova O et al.

Genes, 2023

Mild FVII deficiency - Correlation between genotype and phenotype.

Fraser C et al.

Haemophilia : the Official Journal of the World Federation of Hemophilia, 2023

Extensive genetic screening of Iranian Factor FVII-deficient individuals unraveled several novel mutations and postulated founder effects in some cases.

Ravanbod S et al.

Research and Practice in Thrombosis and Haemostasis, 2023

Cardiovascular Pharmacogenomics: An Update on Clinical Studies of Antithrombotic Drugs in Brazilian Patients.

Hirata TDC et al.

Molecular Diagnosis & Therapy, 2021

Contribution of factor VII polymorphisms to coagulopathy in patients with isolated traumatic brain injury.

Fang J et al.

Clinical Neurology and Neurosurgery, 2021

The EAHAD blood coagulation factor VII variant database.

Giansily-Blaizot M et al.

Human Mutation, 2020

Factor VII Gene Defects: Review of Functional Studies and Their Clinical Implications

Shahbazi S et al.

Iranian Biomedical Journal, 2019

Genetic polymorphisms in the FVII gene is associated with lower extremity deep venous thrombosis: A case-control study.

Liu JW et al.

Journal of Cellular Biochemistry, 2018

Coagulation factor VII gene polymorphisms are not associated with the occurrence or the survival of hepatocellular carcinoma: a report of 37 cases.

Lin CC et al.

Cancer Biology & Medicine, 2018

The Impact of Genetic and Non-Genetic Factors on Warfarin Dose Prediction in MENA Region: A Systematic Review.

Bader LA et al.

Plos One, 2016

Lack of association between potential prothrombotic genetic risk factors and arterial and venous thrombosis.

Evangelista FC et al.

Genetics and Molecular Research : Gmr, 2015

Association between the -402GA, -401GT, and -323ins10-bp polymorphisms of factor VII gene and breast cancer.

Eroğlu A et al.

Breast Cancer (tokyo, Japan), 2011

Prediction of phenprocoumon maintenance dose and phenprocoumon plasma concentration by genetic and non-genetic parameters.

Geisen C et al.

European Journal of Clinical Pharmacology, 2011

Impact of pharmacokinetic (CYP2C9) and pharmacodynamic (VKORC1, F7, GGCX, CALU, EPHX1) gene variants on the initiation and maintenance phases of phenprocoumon therapy.

Luxembourg B et al.

Thrombosis and Haemostasis, 2011

Haplotype and genotype effects of the F7 gene on circulating factor VII, coagulation activation markers and incident coronary heart disease in UK men.

Ken-Dror G et al.

Journal of Thrombosis and Haemostasis : Jth, 2010

No significant association between the promoter region polymorphisms of factor VII gene and risk of venous thrombosis in cancer patients.

Eroğlu A et al.

Experimental Oncology, 2010

Different evolutionary histories of the coagulation factor VII gene in human populations?

Athanasiadis G et al.

Annals of Human Genetics, 2010

The F7 gene and clotting factor VII levels: dissection of a human quantitative trait locus. 2005.

Soria JM et al.

Human Biology, 2009

Influence of clinical and genetic factors on warfarin dose requirements among Japanese patients.

Ohno M et al.

European Journal of Clinical Pharmacology, 2009

Exploring warfarin pharmacogenomics with the extreme-discordant-phenotype methodology: impact of FVII polymorphisms on stable anticoagulation with warfarin.

Fuchshuber-Moraes M et al.

European Journal of Clinical Pharmacology, 2009

CYP2C9*8 is prevalent among African-Americans: implications for pharmacogenetic dosing.

Scott SA et al.

Pharmacogenomics, 2009

The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study.

Maitland-van der Zee AH et al.

Pharmacogenetics and Genomics, 2009

Factor VII -323 decanucleotide D/I polymorphism in atrial fibrillation: implications for the prothrombotic state and stroke risk.

Roldán V et al.

Annals of Medicine, 2008

Functional analysis of the genetic variability in the F7 gene promoter.

Sabater-Lleal M et al.

Atherosclerosis, 2007

Factor VII coagulant activity, factor VII -670A/C and -402G/A polymorphisms, and risk of venous thromboembolism.

Folsom AR et al.

Journal of Thrombosis and Haemostasis : Jth, 2007

Factor VII polymorphisms influence the plasma response to diets with different fat content, in a healthy Caucasian population.

Fernández de la Puebla RA et al.

Molecular Nutrition & Food Research, 2007

[Genetic testing].

Azuma J et al.

Nihon Rinsho. Japanese Journal of Clinical Medicine, 2007

Coagulation factor VII gene haplotypes, obesity-related traits, and cardiovascular risk in young women.

Reiner AP et al.

Journal of Thrombosis and Haemostasis : Jth, 2007

Association of gene polymorphism with genetic susceptibility to stroke in Asian populations: a meta-analysis.

Banerjee I et al.

Journal of Human Genetics, 2007

Factor VII gene haplotypes and risk of ischemic stroke.

Funk M et al.

Clinical Chemistry, 2006

Microelectronic array system for molecular diagnostic genotyping: Nanogen NanoChip 400 and molecular biology workstation.

Keen-Kim D et al.

Expert Review of Molecular Diagnostics, 2006

Influence of coagulation factor, vitamin K epoxide reductase complex subunit 1, and cytochrome P450 2C9 gene polymorphisms on warfarin dose requirements.

Aquilante CL et al.

Clinical Pharmacology and Therapeutics, 2006

Human F7 sequence is split into three deep clades that are related to FVII plasma levels.

Sabater-Lleal M et al.

Human Genetics, 2006

The F7 gene and clotting factor VII levels: dissection of a human quantitative trait locus.

Soria JM et al.

Human Biology, 2005

Genotyping of the angiotensin I-converting enzyme gene insertion/deletion polymorphism by the TaqMan method.

Koch W et al.

Clinical Chemistry, 2005

Factor VII gene polymorphisms are not associated with myocardial infarction in young women.

Peyvandi F et al.

Journal of Thrombosis and Haemostasis : Jth, 2005

Influence of factor VII gene polymorphisms and environmental factors on plasma coagulation factor VII concentrations in middle-aged women with and without manifest coronary heart disease.

Eriksson-Berg M et al.

Thrombosis and Haemostasis, 2005

The influence of the -401G/T and -402G/A polymorphisms of the coagulation FVII promoter on plasma levels of FVII.

Lindman AS et al.

Thrombosis Research, 2005

Polymorphisms in factor II and factor VII genes modulate oral anticoagulation with warfarin.

D'Ambrosio RL et al.

Haematologica, 2004

Genetic determinants of arterial thrombosis.

Voetsch B et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 2004

A patient homozygous for a Gly354Cys mutation in factor VII that results in severely impaired secretion of the molecule, but not complete deficiency.

Takamiya O et al.

British Journal of Haematology, 2004

Polymorphisms of the coagulation factor VII gene and its plasma levels in relation to acute cerebral infarction differences in allelic frequencies between Chinese Han and European populations.

Kang WY et al.

Chinese Medical Journal, 2004

Coinheritance of Factor V (FV) Leiden enhances thrombin formation and is associated with a mild bleeding phenotype in patients homozygous for the FVII 9726+5G>A (FVII Lazio) mutation.

Castoldi E et al.

Blood, 2003

Complexity of the genetic contribution to factor VII deficiency in two Spanish families: clinical and biological implications.

Sabater-Lleal M et al.

Haematologica, 2003

Prevalence of factor VII deficiency and molecular characterization of the F7 gene in Brazilian patients.

Rodrigues DN et al.

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis, 2003

Oestrogenic repression of human coagulation factor VII expression mediated through an oestrogen response element sequence motif in the promoter region.

Di Bitondo R et al.

Human Molecular Genetics, 2002

Characterization of two novel splice site mutations in human factor VII gene causing severe plasma factor VII deficiency and bleeding diathesis.

Borensztajn K et al.

British Journal of Haematology, 2002

Genetic contribution to factor VII levels in families of patients undergoing coronary arteriography.

Jee SH et al.

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."