Associated Papers
Humanization and functional characterization of enhanced coagulation factor IX variants identified through ancestral sequence reconstruction.
Coyle CW et al.
Journal of Thrombosis and Haemostasis : Jth, 2024
Screening for thrombophilia in patients with thromboangitis obliterans using whole-exome sequencing.
Chen F et al.
Thrombosis Research, 2023
CRISPR-Mediated In Situ Introduction or Integration of F9-Padua in Human iPSCs for Gene Therapy of Hemophilia B.
Tang Q et al.
International Journal of Molecular Sciences, 2023
"iPSC-derived liver organoids and inherited bleeding disorders: Potential and future perspectives".
Roman G et al.
Frontiers in Physiology, 2023
In vitro recovery of FIX clotting activity as a marker of highly functional hepatocytes in a hemophilia B iPSC model.
Luce E et al.
Hepatology (baltimore, Md.), 2022
Fusion of engineered albumin with factor IX Padua extends half-life and improves coagulant activity.
Lombardi S et al.
British Journal of Haematology, 2021
Recombinant Adeno-Associated Viral Vectors Expressing Human Coagulation FIX-E456H Variant in Hemophilia B Mice.
Le Quellec S et al.
Thrombosis and Haemostasis, 2019
Molecular Mechanisms and Determinants of Innovative Correction Approaches in Coagulation Factor Deficiencies.
Balestra D et al.
International Journal of Molecular Sciences, 2019
Specific factor IX mRNA and protein features favor drug-induced readthrough over recurrent nonsense mutations.
Branchini A et al.
Blood, 2017
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