Varaico: Literature-Extracted Genetic Variants

Gene:FADD
Variant:p.S194A
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FADD

NM_003824.4:p.S194A

Associated Papers

The adapter protein FADD provides an alternate pathway for entry into the cell cycle by regulating APC/C-Cdh1 E3 ubiquitin ligase activity.

Awadia S et al.

The Journal of Biological Chemistry, 2023

Constitutive phosphorylation mutation in Fas-associated death domain (FADD) results in early cell cycle defects.

Osborn SL et al.

The Journal of Biological Chemistry, 2007

Cell cycle effects by C-FADD depend on its C-terminal phosphorylation site.

Alappat EC et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."