Varaico: Literature-Extracted Genetic Variants

Gene:FAM72A
Variant:p.W125R
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FAM72A

NM_001123168.3:p.W125R

Associated Papers

FAM72A degrades UNG2 through the GID/CTLH complex to promote mutagenic repair during antibody maturation.

Barbulescu P et al.

Nature Communications, 2024

A redox-sensitive iron-sulfur cluster in murine FAM72A controls its ability to degrade the nuclear form of uracil-DNA glycosylase.

Stewart JA et al.

Dna Repair, 2022

FAM72A antagonizes UNG2 to promote mutagenic repair during antibody maturation.

Feng Y et al.

Nature, 2021

Fam72a enforces error-prone DNA repair during antibody diversification.

Rogier M et al.

Nature, 2021

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."