Associated Papers
GJB6 missense variant in a Labrador Retriever with paw pad hyperkeratosis.
Rietmann SJ et al.
Animal Genetics, 2026
Mutations within the predicted fragment-binding region of FAM83G/SACK1G abolish its interaction with the Ser/Thr kinase CK1α.
Utgés JS et al.
Open Biology, 2026
PCR-based detection of hereditary mutations in SLC2A9, BTBD17, and NECAP1 among native Korean dog breeds.
Kang M et al.
Journal of Veterinary Science, 2025
The contribution of native protein complexes to targeted protein degradation.
Glennie L et al.
Biorxiv : the Preprint Server for Biology, 2025
Expanding phenotypic insights of palmoplantar keratodermas based on novel FAM83G variants.
van Gisbergen MW et al.
The British Journal of Dermatology, 2025
A novel FAM83G variant from palmoplantar keratoderma patient disrupts WNT signalling via loss of FAM83G-CK1α interaction.
Glennie L et al.
Open Biology, 2024
Genome sequencing of 2000 canids by the Dog10K consortium advances the understanding of demography, genome function and architecture.
Meadows JRS et al.
Genome Biology, 2023
Inheritance of Monogenic Hereditary Skin Disease and Related Canine Breeds.
Marín-García PJ et al.
Veterinary Sciences, 2022
Genetics of inherited skin disorders in dogs.
Leeb T et al.
Veterinary Journal (london, England : 1997), 2022
FAM83G/Fam83g genetic variants affect canine and murine hair formation.
Balmer P et al.
Experimental Dermatology, 2019
Pathogenic FAM83G palmoplantar keratoderma mutations inhibit the PAWS1:CK1α association and attenuate Wnt signalling.
Wu KZL et al.
Wellcome Open Research, 2019
The FAM83 family of proteins: from pseudo-PLDs to anchors for CK1 isoforms.
Bozatzi P et al.
Biochemical Society Transactions, 2018
Recessive Mutation in FAM83G Associated with Palmoplantar Keratoderma and Exuberant Scalp Hair.
Maruthappu T et al.
The Journal of Investigative Dermatology, 2018
PAWS1 controls Wnt signalling through association with casein kinase 1α.
Bozatzi P et al.
Embo Reports, 2018
Genetic testing in veterinary dermatology.
Leeb T et al.
Veterinary Dermatology, 2017
Whole-Genome Sequencing of a Canine Family Trio Reveals a FAM83G Variant Associated with Hereditary Footpad Hyperkeratosis.
Sayyab S et al.
G3 (bethesda, Md.), 2016
A mutation in the FAM83G gene in dogs with hereditary footpad hyperkeratosis (HFH).
Drögemüller M et al.
Plos Genetics, 2014