Associated Papers
Pathogenic variation in human DNA damage repair genes was originated from the evolutionary process of modern humans.
Li J et al.
Genes & Diseases, 2026
Possible link between the apparently pathogenic FANCI variant and beneficial effects in sports performance.
Berdyński M et al.
Frontiers in Genetics, 2026
Pathogenic variants in human DNA damage repair genes mostly arose in recent human history.
Zhao B et al.
Bmc Cancer, 2024
The evolutionary impact of childhood cancer on the human gene pool.
Stoltze UK et al.
Nature Communications, 2024
Pathogenic variants in human DNA damage repair genes mostly arose after the latest human out-of-Africa migration.
He J et al.
Frontiers in Genetics, 2024
Molecular Genetic Characteristics of FANCI, a Proposed New Ovarian Cancer Predisposing Gene.
Fierheller CT et al.
Genes, 2023
FANCI functions as a repair/apoptosis switch in response to DNA crosslinks.
Shah RB et al.
Developmental Cell, 2021
The causes of Fanconi anemia in South Asia and the Middle East: A case series and review of the literature.
Thompson AS et al.
Molecular Genetics & Genomic Medicine, 2021
Structure of the FA core ubiquitin ligase closing the ID clamp on DNA.
Wang S et al.
Nature Structural & Molecular Biology, 2021
Structural insight into FANCI-FANCD2 monoubiquitination.
Li L et al.
Essays in Biochemistry, 2020
Differential functions of FANCI and FANCD2 ubiquitination stabilize ID2 complex on DNA.
Rennie ML et al.
Embo Reports, 2020
DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.
Wang R et al.
Nature, 2020
TAPES: A tool for assessment and prioritisation in exome studies.
Xavier A et al.
Plos Computational Biology, 2019
Toward automation of germline variant curation in clinical cancer genetics.
Ravichandran V et al.
Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2019
CharGer: clinical Characterization of Germline variants.
Scott AD et al.
Bioinformatics (oxford, England), 2019
Novel FANCI mutations in Fanconi anemia with VACTERL association.
Savage SA et al.
American Journal of Medical Genetics. Part A, 2016
Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA.
Longerich S et al.
Nucleic Acids Research, 2014
The Fanconi anemia DNA repair pathway: structural and functional insights into a complex disorder.
Walden H et al.
Annual Review of Biophysics, 2014
FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures.
Yuan F et al.
The Journal of Biological Chemistry, 2009
Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair.
Smogorzewska A et al.
Cell, 2007