Varaico: Literature-Extracted Genetic Variants

Gene:FAS
Variant:p.Y291D
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FAS

NM_000043.6:p.Y291D

Associated Papers

Synthetic receptor platform to identify loss-of-function single nucleotide variants and designed mutants in the death receptor Fas/CD95.

Minafra AR et al.

The Journal of Biological Chemistry, 2023

An Evolution-Guided Analysis Reveals a Multi-Signaling Regulation of Fas by Tyrosine Phosphorylation and its Implication in Human Cancers.

Chakrabandhu K et al.

Plos Biology, 2016

The Fas-FADD death domain complex structure unravels signalling by receptor clustering.

Scott FL et al.

Nature, 2009

19118384 (PubMed )
Supplement: NIHMS76742-supplement-1.pdf
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