Varaico: Literature-Extracted Genetic Variants

Gene:FASLG
Variant:p.*282Q
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FASLG

NM_000639.3:p.*282Q

Associated Papers

Genomic instability in ovarian cancer: Through the lens of single nucleotide polymorphisms.

Canchi Sistla H et al.

Clinica Chimica Acta; International Journal of Clinical Chemistry, 2025

Prediction of esophageal cancer risk based on genetic variants and environmental risk factors in Chinese population.

Liu H et al.

Bmc Cancer, 2024

38755535 (PubMed )
Supplement: 12885_2024_12370_MOESM3_ESM.docx

The role of FASL, BCL-2 and BAX polymorphisms in brazilian patients with prostate cancer and benign prostatic hyperplasia.

da Silva Lawisch GK et al.

Molecular Biology Reports, 2022

Prioritization and Meta-analysis of regulatory SNPs identified IL6, TGFB1, TLR9 and MMP7 as significantly associated with cervical cancer.

Das AP et al.

Cytokine, 2022

Fas cell surface death receptor/Fas ligand genetic variants in gastric cancer patients: A case-control study.

Asgari R et al.

The Indian Journal of Medical Research, 2022

Single nucleotide polymorphisms and the risk of developing a second primary cancer among head and neck cancer patients: a systematic literature review and meta-analysis.

Hoxhaj I et al.

Bmc Cancer, 2021

Impact of Fas/Fasl Gene Polymorphisms on Susceptibility Risk and Imatinib Mesylate Treatment Response in Chronic Myeloid Leukaemia Patients.

Annuar AA et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2021

Pharmacogenetics of trough serum anti-TNF levels in paediatric inflammatory bowel disease.

Salvador-Martín S et al.

British Journal of Clinical Pharmacology, 2021

Effect of PTPN22, FAS/FASL, IL2RA and CTLA4 genetic polymorphisms on the risk of developing alopecia areata: A systematic review of the literature and meta-analysis.

Gil-Quiñones SR et al.

Plos One, 2021

Cumulative Evidence for Associations between Genetic Variants and Risk of Esophageal Cancer.

Li G et al.

Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology, 2020

31969372 (PubMed )
Supplement: 10559965epi191281-sup-230715_3_supp_6000458_q3kstt.docx

Identification of a FAS/FASL haplotype associated with endometriosis in Iranian patients.

Akhavan Sales Z et al.

Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology, 2020

Fas and FasL promoter polymorphisms and susceptibility to HBV infection: A systematic review and meta-analysis.

Mohammadi A et al.

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases, 2019

Genetic predictors of long-term response and trough levels of infliximab in crohn's disease.

Salvador-Martín S et al.

Pharmacological Research, 2019

Alopecia Areata. Current situation and perspectives.

Juárez-Rendón KJ et al.

Archivos Argentinos De Pediatria, 2017

Genetic Polymorphisms of Fas/FasL Promoter Associated with Hepatitis C cirrhosis and HCC

Abed S et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2017

Digging more in the genetic risk prediction of hepatitis C virus epidemic in Egypt: Apoptosis genes polymorphisms in the susceptibility of hepatitis C virus and association with viral load.

Khalifa RH et al.

Virus Research, 2017

Fas/FasL gene polymorphism in patients with Hashimoto's thyroiditis in Turkish population.

Erdogan M et al.

Journal of Endocrinological Investigation, 2017

Cervical Carcinogenesis and Immune Response Gene Polymorphisms: A Review.

Mehta AM et al.

Journal of Immunology Research, 2017

Polymorphisms of extrinsic death receptor apoptotic genes (FAS -670 G>A, FASL -844 T>C) in coronary artery disease.

Kishore Kumar G et al.

Apoptosis : an International Journal on Programmed Cell Death, 2016

Association of promoter polymorphisms of Fas -FasL genes with development of Chronic Myeloid Leukemia.

Edathara PM et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2016

Quantitative assessment of the association between Fas/FasL gene polymorphism and susceptibility to esophageal carcinoma in a north Chinese population.

Zhang M et al.

Cancer Medicine, 2016

Significant association between FasL gene -844T/C polymorphism and risk to hepatocellular carcinoma in Egyptian patients.

Khalifa RH et al.

Immunology Letters, 2016

Associations between FAS rs2234767 and FASL rs763110 polymorphisms and the risk of lung cancer: a meta-analysis of 39,736 subjects.

Yu X et al.

Oncotargets and Therapy, 2016

Apoptotic variants as predictors of risk of oropharyngeal cancer recurrence after definitive radiotherapy.

Zhang F et al.

International Journal of Cancer, 2015

The role of functional polymorphisms in immune response genes as biomarkers of bacille Calmette-Guérin (BCG) immunotherapy outcome in bladder cancer: establishment of a predictive profile in a Southern Europe population.

Lima L et al.

Bju International, 2015

The combined risks of reduced or increased function variants in cell death pathway genes differentially influence cervical cancer risk and herpes simplex virus type 2 infection among black Africans and the Mixed Ancestry population of South Africa.

Chattopadhyay K et al.

Bmc Cancer, 2015

FAS -670A>G genetic polymorphism Is associated with Treatment Resistant Depression.

Santos M et al.

Journal of Affective Disorders, 2015

A First Step toward Personalized Medicine in Osteosarcoma: Pharmacogenetics as Predictive Marker of Outcome after Chemotherapy-Based Treatment.

Hagleitner MM et al.

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2015

FasL -844T/C and Fas -1377G/A: mutations of pulmonary adenocarcinoma in South China and their clinical significances.

Zhao H et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2015

Association between the CTLA-4, CD226, FAS polymorphisms and rheumatoid arthritis susceptibility: a meta-analysis.

Lee YH et al.

Human Immunology, 2015

Prognostic role of apoptosis-related gene functional variants in advanced non-small-cell lung cancer patients treated with first-line platinum-based chemotherapy.

Tao KY et al.

Oncotargets and Therapy, 2015

Cyclooxygenase-2 polymorphisms and bladder cancer risk: a meta-analysis based on case-control studies.

Wan GX et al.

International Journal of Clinical and Experimental Medicine, 2015

Polymorphisms of the apoptosis-related FAS and FAS ligand genes in keratoconus and Fuchs endothelial corneal dystrophy.

Synowiec E et al.

The Tohoku Journal of Experimental Medicine, 2014

LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas.

Tsai LH et al.

Oncogene, 2014

Association between FAS and FASL genetic variants and risk of primary brain tumor.

Dalan AB et al.

The International Journal of Neuroscience, 2014

Possible association of FAS and FASLG polymorphisms with the risk of idiopathic azoospermia in southeast Turkey.

Balkan M et al.

Genetic Testing and Molecular Biomarkers, 2014

Associations between Fas/FasL polymorphisms and susceptibility to cervical cancer: a meta-analysis.

Wang GQ et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

Quantitative assessment of the association between three polymorphisms in FAS and FASL gene and breast cancer risk.

Wang Z et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

FASLG T844C polymorphism and susceptibility to breast cancer: a meta-analysis.

Huang O et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2014

FasL gene -844T/C mutation of esophageal cancer in South China and its clinical significance.

Zhao H et al.

Scientific Reports, 2014

FASL polymorphism is associated with response to bacillus Calmette-Guérin immunotherapy in bladder cancer.

Lima L et al.

Urologic Oncology, 2014

Death receptor (DR4) haplotypes are associated with increased susceptibility of gallbladder carcinoma in north Indian population.

Rai R et al.

Plos One, 2014

Association of the polymorphisms in the Fas/FasL promoter regions with cancer susceptibility: a systematic review and meta-analysis of 52 studies.

Xu Y et al.

Plos One, 2014

Multi-loci analysis reveals the importance of genetic variations in sensitivity of platinum-based chemotherapy in non-small-cell lung cancer.

Liu L et al.

Molecular Carcinogenesis, 2013

Evaluation of death pathway genes FAS and FASL polymorphisms in chronic HBV infection.

Zamani AG et al.

International Journal of Immunogenetics, 2013

Functional polymorphisms in cell death pathway genes FAS and FAS ligand and risk of alopecia areata.

Kalkan G et al.

Archives of Dermatological Research, 2013

Relation of the Fas and FasL gene polymorphisms with susceptibility to and severity of rheumatoid arthritis.

Yıldır S et al.

Rheumatology International, 2013

Apoptosis-related Fas and FasL gene polymorphisms' associations with knee osteoarthritis.

Sezgin M et al.

Rheumatology International, 2013

Associations of three common polymorphisms in CD95 and CD95L promoter regions with gastric cancer risk.

Li F et al.

Tumour Biology : the Journal of the International Society for Oncodevelopmental Biology and Medicine, 2013

Functional polymorphisms in FAS and FASL contribute to risk of squamous cell carcinoma of the larynx and hypopharynx in a Chinese population.

Wang J et al.

Gene, 2013

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