Varaico: Literature-Extracted Genetic Variants

Gene:FBXW7
Variant:p.E693K
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FBXW7

NM_001349798.2:p.E693K

Associated Papers

A Comprehensive Assessment of Genetic and Epigenetic Alterations Identifies Frequent Variations Impacting Six Prototypic SCF Complex Members.

Campos Gudiño R et al.

International Journal of Molecular Sciences, 2021

Genomic origin and intratumor heterogeneity revealed by sequencing on carcinomatous and sarcomatous components of pulmonary sarcomatoid carcinoma.

Liu X et al.

Oncogene, 2021

Copy number signatures and mutational processes in ovarian carcinoma.

Macintyre G et al.

Nature Genetics, 2018

30104763 (PubMed )
Supplement: NIHMS78219-supplement-3.xlsx › mutated_cases

The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors.

Stehr H et al.

Molecular Cancer, 2011

21575214 (PubMed )
Supplement: 1476-4598-10-54-S3.XLS › mutations.txt

NOTCH1 and/or FBXW7 mutations predict for initial good prednisone response but not for improved outcome in pediatric T-cell acute lymphoblastic leukemia patients treated on DCOG or COALL protocols.

Zuurbier L et al.

Leukemia, 2010

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

Akhoondi S et al.

Cancer Research, 2007

Mutational analysis of the hCDC4 gene in gastric carcinomas.

Lee JW et al.

European Journal of Cancer (oxford, England : 1990), 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."