Varaico: Literature-Extracted Genetic Variants

Gene:FBXW7
Variant:p.S668fs
Back to variants list

FBXW7

NM_001349798.2:p.S668fs

Associated Papers

Maritoclax Overcomes FBW7 Deficiency-Driven Irinotecan Resistance in Colorectal Cancer by Targeting MCL1.

Lin Q et al.

Cancer Medicine, 2025

Multicenter In-House Evaluation of an Amplicon-Based Next-Generation Sequencing Panel for Comprehensive Molecular Profiling.

Jantus-Lewintre E et al.

Molecular Diagnosis & Therapy, 2025

39798063 (PubMed )
Supplement: 40291_2024_766_MOESM2_ESM.xlsx › S1c-Control_D_2_HD827

Comprehensive genomic characterization of sporadic synchronous colorectal cancer: Implications for treatment optimization and clinical outcome.

Yang LP et al.

Cell Reports. Medicine, 2023

37794586 (PubMed )
Supplement: mmc4.xlsx › TCGA_path_oncokb

NTRK fusion positive colorectal cancer is a unique subset of CRC with high TMB and microsatellite instability.

Wang H et al.

Cancer Medicine, 2022

35506567 (PubMed )
Supplement: CAM4-11-2541-s004.pdf

Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations.

Thirimanne HN et al.

Elife, 2022

35225231 (PubMed )
Supplement: elife-74338-fig5-data2.xlsx › Fbw7_Mutant

Analytical and clinical validation of an amplicon-based next generation sequencing assay for ultrasensitive detection of circulating tumor DNA.

Poh J et al.

Plos One, 2022

35486650 (PubMed )
Supplement: pone.0267389.s008.xlsx › S1_Table

A Case of Microsatellite Instability-High Colon Cancer in a Young Woman With Familial Adenomatous Polyposis.

Blum SM et al.

Journal of the National Comprehensive Cancer Network : Jnccn, 2021

FBXW7 deletion contributes to lung tumor development and confers resistance to gefitinib therapy.

Xiao Y et al.

Molecular Oncology, 2018

29633504 (PubMed )
Supplement: MOL2-12-883-s002.xlsx › Sheet1
Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."