Varaico: Literature-Extracted Genetic Variants

Gene:FBXW7
Variant:p.D527G
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FBXW7

NM_001349798.2:p.D527G

Associated Papers

The Role of FBXW7 in Gynecologic Malignancies.

Di Fiore R et al.

Cells, 2023

Clinical significance of FBXW7 loss of function in human cancers.

Fan J et al.

Molecular Cancer, 2022

PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia.

Govaerts I et al.

Journal of Hematology & Oncology, 2021

34167562 (PubMed )
Supplement: 13045_2021_1114_MOESM1_ESM.xlsx › Sheet1

Loss of FBXW7-mediated degradation of BRAF elicits resistance to BET inhibitors in adult T cell leukemia cells.

Yeh CH et al.

Molecular Cancer, 2020

Development and validation of a targeted gene sequencing panel for application to disparate cancers.

McCabe MJ et al.

Scientific Reports, 2019

31745186 (PubMed )
Supplement: 41598_2019_52000_MOESM2_ESM.xlsx › Sheet1

FBXW7: a critical tumor suppressor of human cancers.

Yeh CH et al.

Molecular Cancer, 2018

Oncogenic mutations in the FBXW7 gene of adult T-cell leukemia patients.

Yeh CH et al.

Proceedings of the National Academy of Sciences of the United States of America, 2016

Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers.

Maser RS et al.

Nature, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."