Varaico: Literature-Extracted Genetic Variants

Gene:FBXW7
Variant:p.S462A
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FBXW7

NM_001349798.2:p.S462A

Associated Papers

The SCF-FBXW7 E3 ubiquitin ligase triggers degradation of histone 3 lysine 4 methyltransferase complex component WDR5 to prevent mitotic slippage.

Hänle-Kreidler S et al.

The Journal of Biological Chemistry, 2022

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."