Varaico: Literature-Extracted Genetic Variants

Gene:FBXW7
Variant:p.L403fs
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FBXW7

NM_001349798.2:p.L403fs

Associated Papers

Common gene mutations in 103 authenticated colorectal cancer cell lines.

Kranjec C et al.

Oncogenesis, 2026

41593049 (PubMed )
Supplement: 41389_2026_599_MOESM2_ESM.xlsx › Supplementary_Table_9

FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2.

Jiménez-Izquierdo R et al.

Cell Death & Disease, 2023

Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12.

Khan OM et al.

Nature Communications, 2021

FBW7 mutations mediate resistance of colorectal cancer to targeted therapies by blocking Mcl-1 degradation.

Tong J et al.

Oncogene, 2017

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."