Varaico: Literature-Extracted Genetic Variants

Gene:FBXW7
Variant:p.S227A
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FBXW7

NM_001349798.2:p.S227A

Associated Papers

FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2.

Jiménez-Izquierdo R et al.

Cell Death & Disease, 2023

36934104 (PubMed )
Supplement: 41419_2023_5724_MOESM2_ESM.pdf

PI3K-dependent phosphorylation of Fbw7 modulates substrate degradation and activity.

Schülein C et al.

Febs Letters, 2011

Serum- and glucocorticoid-inducible kinase 1 (SGK1) controls Notch1 signaling by downregulation of protein stability through Fbw7 ubiquitin ligase.

Mo JS et al.

Journal of Cell Science, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."