Varaico: Literature-Extracted Genetic Variants

Gene:FBXW7
Variant:p.T205A
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FBXW7

NM_001349798.2:p.T205A

Associated Papers

Arachidonic acid released by PIK3CA mutant tumor cells triggers malignant transformation of colonic epithelium by inducing chromatin remodeling.

He B et al.

Cell Reports. Medicine, 2024

FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2.

Jiménez-Izquierdo R et al.

Cell Death & Disease, 2023

36934104 (PubMed )
Supplement: 41419_2023_5724_MOESM2_ESM.pdf

ERK kinase phosphorylates and destabilizes the tumor suppressor FBW7 in pancreatic cancer.

Ji S et al.

Cell Research, 2015

Negative regulation of the stability and tumor suppressor function of Fbw7 by the Pin1 prolyl isomerase.

Min SH et al.

Molecular Cell, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."