Varaico: Literature-Extracted Genetic Variants

Gene:FBXW7
Variant:p.K11R
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FBXW7

NM_001349798.2:p.K11R

Associated Papers

Proteasomal degradation of the tumour suppressor FBW7 requires branched ubiquitylation by TRIP12.

Khan OM et al.

Nature Communications, 2021

The Human Cytomegalovirus pUL145 Isoforms Act as Viral DDB1-Cullin-Associated Factors to Instruct Host Protein Degradation to Impede Innate Immunity.

Le-Trilling VTK et al.

Cell Reports, 2020

Temsirolimus therapy in a patient with lung adenocarcinoma harboring an FBXW7 mutation.

Villaruz LC et al.

Lung Cancer (amsterdam, Netherlands), 2014

FBXW7/hCDC4 is a general tumor suppressor in human cancer.

Akhoondi S et al.

Cancer Research, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."