Varaico: Literature-Extracted Genetic Variants

Gene:FCGR3A
Variant:p.F176V
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FCGR3A

NM_000569.8:p.F176V

Associated Papers

FCGR2C Q13 and FCGR3A V176 alleles jointly associate with worse natural killer cell-mediated antibody-dependent cellular cytotoxicity and microvascular inflammation in kidney allograft antibody-mediated rejection.

Bailly E et al.

American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2025

Genomic and clinical characterization of pediatric lymphoepithelioma-like carcinoma.

Que Y et al.

Journal of Translational Medicine, 2024

39633439 (PubMed )
Supplement: 12967_2024_5921_MOESM7_ESM.xlsx › 11newmerge

Phenotype driven molecular genetic test recommendation for diagnosing pediatric rare disorders.

Chen F et al.

Npj Digital Medicine, 2024

39572625 (PubMed )
Supplement: 41746_2024_1331_MOESM2_ESM.xlsx › Supplementary_Data_6

Fc gamma receptors: Their evolution, genomic architecture, genetic variation, and impact on human disease.

Frampton S et al.

Immunological Reviews, 2024

Genetic variability of three common NK and γδ T cell receptor genes (FCγ3R, NCR3, and DNAM-1) and their role in Polish patients with rheumatoid arthritis and ankylosing spondylitis.

Biały S et al.

Immunologic Research, 2024

FCGR2/3 polymorphisms are associated with susceptibility to Kawasaki disease but do not predict intravenous immunoglobulin resistance and coronary artery aneurysms.

Uittenbogaard P et al.

Frontiers in Immunology, 2024

Meta-analysis fine-mapping is often miscalibrated at single-variant resolution.

Kanai M et al.

Cell Genomics, 2022

High-affinity FcγRIIIa genetic variants and potent NK cell-mediated antibody-dependent cellular cytotoxicity (ADCC) responses contributing to severe COVID-19.

Vietzen H et al.

Genetics in Medicine : Official Journal of the American College of Medical Genetics, 2022

The FCGR2A rs1801274 polymorphism was associated with the risk of death among COVID-19 patients.

López-Martínez R et al.

Clinical Immunology (orlando, Fla.), 2022

FCGR Genetic Variation in Two Populations From Ecuador Highlands-Extensive Copy-Number Variation, Distinctive Distribution of Functional Polymorphisms, and a Novel, Locally Common, Chimeric FCGR3B/A (CD16B/A) Gene.

Moraru M et al.

Frontiers in Immunology, 2021

Integrated Genomic, Functional, and Prognostic Characterization of Atypical Chronic Myeloid Leukemia.

Fontana D et al.

Hemasphere, 2020

33196013 (PubMed )
Supplement: hs9-4-e497-s005.xlsx › Sheet1

Hereditary Haemorrhagic Telangiectasia (HHT) Marked by ACVRL1C1120T Variant Displays Hypopigmented Naevi and Frequent Bleeding Episodes if CYP2C9 Co-Mutated: Clinical Notes & Rationale of Patient Registry.

Minarik L et al.

Folia Biologica, 2020

Chronic HIV-1 Infection Alters the Cellular Distribution of FcγRIIIa and the Functional Consequence of the FcγRIIIa-F158V Variant.

Phaahla NG et al.

Frontiers in Immunology, 2019

Novel identified associations of RGS1 and RASGRP1 variants in IgA Nephropathy.

Zhou XJ et al.

Scientific Reports, 2016

27804980 (PubMed )
Supplement: srep35781-s1.xls › old_genes

Rheumatoid Arthritis: The Stride from Research to Clinical Practice.

Chung IM et al.

International Journal of Molecular Sciences, 2016

Accurate interrogation of FCGR3A rs396991 in European and Asian populations using a widely available TaqMan genotyping method.

Murphy KE et al.

Pharmacogenetics and Genomics, 2015

Advances in lupus genetics and epigenetics.

Deng Y et al.

Current Opinion in Rheumatology, 2014

Fcγ receptor IIIa single-nucleotide polymorphisms and haplotypes affect human IgG binding and are associated with lupus nephritis in African Americans.

Dong C et al.

Arthritis & Rheumatology (hoboken, N.j.), 2014

Gene-function studies in systemic lupus erythematosus.

Crispín JC et al.

Nature Reviews. Rheumatology, 2013

The genetics of systemic lupus erythematosus and implications for targeted therapy.

Sestak AL et al.

Annals of the Rheumatic Diseases, 2011

Genetic susceptibility to systemic lupus erythematosus in the genomic era.

Deng Y et al.

Nature Reviews. Rheumatology, 2010

Role of Fc gamma receptor IIb polymorphism in the genetic background of systemic lupus erythematosus: insights from Asia.

Tsuchiya N et al.

Autoimmunity, 2005

Association of Fcgamma receptor IIb polymorphism with susceptibility to systemic lupus erythematosus in Chinese: a common susceptibility gene in the Asian populations.

Chu ZT et al.

Tissue Antigens, 2004

Association of Fcgamma receptor IIb and IIIb polymorphisms with susceptibility to systemic lupus erythematosus in Thais.

Siriboonrit U et al.

Tissue Antigens, 2003

Studies on the association of Fc gamma receptor IIA, IIB, IIIA and IIIB polymorphisms with rheumatoid arthritis in the Japanese: evidence for a genetic interaction between HLA-DRB1 and FCGR3A.

Kyogoku C et al.

Genes and Immunity, 2002

Relevance of systemic lupus erythematosus nephritis animal models to human disease.

Foster MH

Seminars in Nephrology, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."