Associated Papers
Flap Endonuclease 1 Mutations A159V and E160D Cause Genomic Instability by Slowing Reaction on Double-Flap Substrates.
Algasaier SI et al.
Biochemistry, 2018
Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability.
Tsutakawa SE et al.
Nature Communications, 2017
Okazaki fragment maturation involves α-segment error editing by the mammalian FEN1/MutSα functional complex.
Liu S et al.
The Embo Journal, 2015
Fen1 mutations result in autoimmunity, chronic inflammation and cancers.
Zheng L et al.
Nature Medicine, 2007
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