Varaico: Literature-Extracted Genetic Variants

Gene:FEN1
Variant:p.D179A
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FEN1

NM_004111.6:p.D179A

Associated Papers

Structure and repair of replication-coupled DNA breaks.

Pavani R et al.

Science (new York, N.y.), 2024

Flap endonuclease Rad27 cleaves the RNA of R-loop structures to suppress telomere recombination.

Liu CC et al.

Nucleic Acids Research, 2023

Phosphate steering by Flap Endonuclease 1 promotes 5'-flap specificity and incision to prevent genome instability.

Tsutakawa SE et al.

Nature Communications, 2017

Functional analysis of human FEN1 in Saccharomyces cerevisiae and its role in genome stability.

Greene AL et al.

Human Molecular Genetics, 1999

Functional analysis of point mutations in human flap endonuclease-1 active site.

Shen B et al.

Nucleic Acids Research, 1997

Essential amino acids for substrate binding and catalysis of human flap endonuclease 1.

Shen B et al.

The Journal of Biological Chemistry, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."