Varaico: Literature-Extracted Genetic Variants

Gene:FEN1
Variant:p.L209P
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FEN1

NM_004111.6:p.L209P

Associated Papers

Exploring homologous recombination repair and base excision repair pathway genes for possible diagnostic markers in hematologic malignancies.

Abbasi SF et al.

Molecular Genetics and Genomics : Mgg, 2023

Small-Molecule Inhibitors Targeting FEN1 for Cancer Therapy.

Yang F et al.

Biomolecules, 2022

Enhanced Activity of Variant DNA Polymerase β (D160G) Contributes to Cisplatin Therapy by Impeding the Efficiency of NER.

Wang M et al.

Molecular Cancer Research : Mcr, 2019

31350308 (PubMed )
Supplement: 15417786mcr190482-sup-221944_2_supp_5635487_p1d1dq.docx

Around and beyond 53BP1 Nuclear Bodies.

Fernandez-Vidal A et al.

International Journal of Molecular Sciences, 2017

The FEN1 L209P mutation interferes with long-patch base excision repair and induces cellular transformation.

Sun H et al.

Oncogene, 2017

Targeting DNA Flap Endonuclease 1 to Impede Breast Cancer Progression.

He L et al.

Ebiomedicine, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."