Varaico: Literature-Extracted Genetic Variants

Gene:FEN1
Variant:p.G240D
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FEN1

NM_004111.6:p.G240D

Associated Papers

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes.

Yamaji T et al.

Febs Letters, 2025

Roles for the Rad27 Flap Endonuclease in Mitochondrial Mutagenesis and Double-Strand Break Repair in Saccharomyces cerevisiae.

Nagarajan P et al.

Genetics, 2017

Saccharomyces cerevisiae flap endonuclease 1 uses flap equilibration to maintain triplet repeat stability.

Liu Y et al.

Molecular and Cellular Biology, 2004

The Fen1 extrahelical 3'-flap pocket is conserved from archaea to human and regulates DNA substrate specificity.

Friedrich-Heineken E et al.

Nucleic Acids Research, 2004

Analysis of human flap endonuclease 1 mutants reveals a mechanism to prevent triplet repeat expansion.

Liu Y et al.

The Journal of Biological Chemistry, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."